Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
6th Edition
ISBN: 9780815344322
Author: Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher: W. W. Norton & Company
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Chapter 19, Problem 6P
Summary Introduction

To explain: How is it necessary to use Fab fragments to block cell aggregation.

Introduction: Cell-cell adhesions play an important role in maintaining the architecture of various tissues. The homophilic and heterophilic adhesion of cells is mediated by many cell-surface proteins known as cell adhesion molecules (CAMs). CAMs were identified originally through anitbodies raised against cell-surface components to block cell aggregation.

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