How can the two tight junction strands remain even after the disappearance of claudin-4 caused due to incubation of MDCK epithelial sheet with C-terminal toxin fragment. Concept introduction: Tight junctions are the type of cell junctions where two adjacent cells join together and constitute the barrier. These are connected by transmembrane proteins including occludins and claudins. Transmembrane proteins form paracellular pores making the junction selectively permeable through which specific molecules pass across tight junctions.

Question

Want to see the full answer?

Answer 1

Question

Chapter 19, Problem 7P

A.

Summary Introduction

To explain: How can the two tight junction strands remain even after the disappearance of claudin-4 caused due to incubation of MDCK epithelial sheet with C-terminal toxin fragment.

Concept introduction: Tight junctions are the type of cell junctions where two adjacent cells join together and constitute the barrier. These are connected by transmembrane proteins including occludins and claudins. Transmembrane proteins form paracellular pores making the junction selectively permeable through which specific molecules pass across tight junctions.

B.

Summary Introduction

To explain: The toxin works when it is added to the basolateral side of the epithelial sheet, but not when added to the apical side.

Concept introduction: Tight junctions are the type of cell junctions where two adjacent cells join together and constitute barrier. These are connected by transmembrane proteins including occludins and claudins. Transmembrane proteins form paracellular pores making the junction selectively permeable through which specific molecules pass across tight junctions.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 2

Question

Chapter 19, Problem 7P

A.

Summary Introduction

To explain: How can the two tight junction strands remain even after the disappearance of claudin-4 caused due to incubation of MDCK epithelial sheet with C-terminal toxin fragment.

Concept introduction: Tight junctions are the type of cell junctions where two adjacent cells join together and constitute the barrier. These are connected by transmembrane proteins including occludins and claudins. Transmembrane proteins form paracellular pores making the junction selectively permeable through which specific molecules pass across tight junctions.

B.

Summary Introduction

To explain: The toxin works when it is added to the basolateral side of the epithelial sheet, but not when added to the apical side.

Concept introduction: Tight junctions are the type of cell junctions where two adjacent cells join together and constitute barrier. These are connected by transmembrane proteins including occludins and claudins. Transmembrane proteins form paracellular pores making the junction selectively permeable through which specific molecules pass across tight junctions.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Chapter 19, Problem 7P

A.

Summary Introduction

To explain: How can the two tight junction strands remain even after the disappearance of claudin-4 caused due to incubation of MDCK epithelial sheet with C-terminal toxin fragment.

Concept introduction: Tight junctions are the type of cell junctions where two adjacent cells join together and constitute the barrier. These are connected by transmembrane proteins including occludins and claudins. Transmembrane proteins form paracellular pores making the junction selectively permeable through which specific molecules pass across tight junctions.

B.

Summary Introduction

To explain: The toxin works when it is added to the basolateral side of the epithelial sheet, but not when added to the apical side.

Concept introduction: Tight junctions are the type of cell junctions where two adjacent cells join together and constitute barrier. These are connected by transmembrane proteins including occludins and claudins. Transmembrane proteins form paracellular pores making the junction selectively permeable through which specific molecules pass across tight junctions.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Chapter 19, Problem 7P

A.

Summary Introduction

To explain: How can the two tight junction strands remain even after the disappearance of claudin-4 caused due to incubation of MDCK epithelial sheet with C-terminal toxin fragment.

Concept introduction: Tight junctions are the type of cell junctions where two adjacent cells join together and constitute the barrier. These are connected by transmembrane proteins including occludins and claudins. Transmembrane proteins form paracellular pores making the junction selectively permeable through which specific molecules pass across tight junctions.

B.

Summary Introduction

To explain: The toxin works when it is added to the basolateral side of the epithelial sheet, but not when added to the apical side.

Concept introduction: Tight junctions are the type of cell junctions where two adjacent cells join together and constitute barrier. These are connected by transmembrane proteins including occludins and claudins. Transmembrane proteins form paracellular pores making the junction selectively permeable through which specific molecules pass across tight junctions.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 5

Chapter 19, Problem 7P

A.

Summary Introduction

To explain: How can the two tight junction strands remain even after the disappearance of claudin-4 caused due to incubation of MDCK epithelial sheet with C-terminal toxin fragment.

Concept introduction: Tight junctions are the type of cell junctions where two adjacent cells join together and constitute the barrier. These are connected by transmembrane proteins including occludins and claudins. Transmembrane proteins form paracellular pores making the junction selectively permeable through which specific molecules pass across tight junctions.

B.

Summary Introduction

To explain: The toxin works when it is added to the basolateral side of the epithelial sheet, but not when added to the apical side.

Concept introduction: Tight junctions are the type of cell junctions where two adjacent cells join together and constitute barrier. These are connected by transmembrane proteins including occludins and claudins. Transmembrane proteins form paracellular pores making the junction selectively permeable through which specific molecules pass across tight junctions.

Answer 6

Chapter 19, Problem 7P

A.

Summary Introduction

To explain: How can the two tight junction strands remain even after the disappearance of claudin-4 caused due to incubation of MDCK epithelial sheet with C-terminal toxin fragment.

Concept introduction: Tight junctions are the type of cell junctions where two adjacent cells join together and constitute the barrier. These are connected by transmembrane proteins including occludins and claudins. Transmembrane proteins form paracellular pores making the junction selectively permeable through which specific molecules pass across tight junctions.

Answer 7

Chapter 19, Problem 7P

A.

Summary Introduction

To explain: How can the two tight junction strands remain even after the disappearance of claudin-4 caused due to incubation of MDCK epithelial sheet with C-terminal toxin fragment.

Concept introduction: Tight junctions are the type of cell junctions where two adjacent cells join together and constitute the barrier. These are connected by transmembrane proteins including occludins and claudins. Transmembrane proteins form paracellular pores making the junction selectively permeable through which specific molecules pass across tight junctions.

Answer 8

B.

Summary Introduction

To explain: The toxin works when it is added to the basolateral side of the epithelial sheet, but not when added to the apical side.

Concept introduction: Tight junctions are the type of cell junctions where two adjacent cells join together and constitute barrier. These are connected by transmembrane proteins including occludins and claudins. Transmembrane proteins form paracellular pores making the junction selectively permeable through which specific molecules pass across tight junctions.

Answer 9

B.

Summary Introduction

To explain: The toxin works when it is added to the basolateral side of the epithelial sheet, but not when added to the apical side.

Concept introduction: Tight junctions are the type of cell junctions where two adjacent cells join together and constitute barrier. These are connected by transmembrane proteins including occludins and claudins. Transmembrane proteins form paracellular pores making the junction selectively permeable through which specific molecules pass across tight junctions.

Answer 10

Expert Solution & Answer

Answer 11

Expert Solution & Answer

Answer 12

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 13

Ch. 19 - Prob. 1P Ch. 19 - Prob. 2P Ch. 19 - Prob. 3P Ch. 19 - Prob. 4P Ch. 19 - Prob. 5P Ch. 19 - Prob. 6P Ch. 19 - Prob. 7P Ch. 19 - Prob. 8P Ch. 19 - Prob. 9P Ch. 19 - Prob. 10P

Concept explainers

Videos

Want to see the full answer?

Chapter 19 Solutions