Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
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Chapter 19, Problem 15TYK
Summary Introduction
To review:
The annotation and determination of human-coding genes by sequencing the genome in animal species that are great in number.
Introduction:
Genes are an important part of the DNA (deoxyribonucleic acid). There are multiple genes present on DNA. Genes are responsible for causing heredity from parents to progeny. The formation of protein is guided by these genes.
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Illustrate about the Map and sequence the genomes of several model organisms used in experimental genetics, including Escherichia coli, Saccharomyces cerevisiae, Caenorhabditis elegans, Drosophila melanogaster, and Mus musculus (mouse).
You are interested in finding out the function of a particular gene in the mouse genome. You have determined the nucleotide sequence of the gene, defined the portion that codes for its protein product, and searched the relevant database for similar sequences; however, neither the gene nor the encoded protein resembles anything previously described. What types of additional information about the gene and the encoded protein would you like to know in order to narrow down its function, and why?
Bioinformatics cana. assist genomics and proteomics.b. compare our genome to that of a primate.c. depend on computer technology.d. match genes with proteins.e. All of these are correct
Chapter 19 Solutions
Biology: The Dynamic Science (MindTap Course List)
Ch. 19.1 - What additional biological questions can be...Ch. 19.2 - What is the principle behind whole-genome shotgun...Ch. 19.2 - Prob. 2SBCh. 19.2 - Prob. 3SBCh. 19.2 - Prob. 4SBCh. 19.3 - Prob. 1SBCh. 19.3 - Prob. 2SBCh. 19.3 - Prob. 3SBCh. 19.4 - Prob. 1SBCh. 19.4 - Prob. 2SB
Ch. 19 - Prob. 1TYKCh. 19 - How do pseudogenes differ from genes? a. They are...Ch. 19 - Prob. 3TYKCh. 19 - Prob. 4TYKCh. 19 - Prob. 5TYKCh. 19 - Prob. 6TYKCh. 19 - About 95% of the average human transcription unit...Ch. 19 - Prob. 8TYKCh. 19 - Prob. 9TYKCh. 19 - When two protein-coding genes have very similar...Ch. 19 - Prob. 11TYKCh. 19 - Prob. 12TYKCh. 19 - Prob. 13TYKCh. 19 - Discuss Concepts The genome of the yeast...Ch. 19 - Prob. 15TYKCh. 19 - Prob. 16TYKCh. 19 - Prob. 17TYKCh. 19 - Below is a sequence of 540 bases from a genome....
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- You have isolated a transposable element from the human genome and have determined its DNA sequence. How would you use this sequence to determine the copy number of the element in the human genome if you just had a computer with an Internet connection? (Hint: see Chapter 14.)arrow_forwardA mouse gene was identified and determined to be required for formation of heart muscle. A gene with a similar sequence was identified in the human genome. What experiment could scientists do to determine if the mouse and human genes have similar functions? A. The scientist could place the normal human gene into normal mice and see if the resulting mice are viable. B. The scientist could search the human genome for genes that encode proteins that are identical to the protein encoded by the mouse gene. C. The scientist could place the normal human gene into mutant mice to see if heart muscle forms in the mouse. D. The scientist could place the mutant mouse gene into humans to see if humans develop without heart muscle.arrow_forwardDescribe how genome-wide association studies have led to new understandings about the structure and function of the genome.arrow_forward
- Not long ago investigators were surprised to learn that more than 95% of a mammalian genome is transcribed, even though less than 2% encodes proteins. What kind of evidence could be used to determine the percentage of the genome that is transcribed?arrow_forwardwhy are the human genome project and ENCODE important and how do they relate to the future of medicine?arrow_forwardDiscuss the role that transposons may have played in the evolution of modern organisms.arrow_forward
- Discuss an example of a human gene and the function of the particular protein molecule it codes for?arrow_forwardSuppose you had funding to do a genome-wide gene expression experiment (20,000 genes). You can use a total of 20 RNA samples. Briefly describe the experiment you would run. In the context of your experiment, what is a false positive? In the context of your experiment, what is a false negativearrow_forwardExplain why exome sequencing can be almost as valuable as genome sequencing. (Explain in your own words)arrow_forward
- The overall goal of the ENCODE Project is a. to sequence the entire genome from many different people. b. to identify all of the functional elements in the human genome. c. to study the expression of selected human genes. d. none of the above.arrow_forwardWhat are the types of transposons? Please explain in detail how transposons contribute to genome evolution.arrow_forwardGenome comparisons have suggested that mouse DNA has mutated about twice as fast as human DNA. What is a possible explanation for this discrepancy? a. Mice are much smaller than humans. b. Mice live in much less sanitary conditions than humans and are therefore exposed to a wider range of mutation-causing substances. c. Mice have a smaller genome size. d. Mice have a much shorter generation time.arrow_forward
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