Chapter 19, Problem 19.62QP

Interpretation Introduction

Interpretation:

The role of a coenzyme in an enzyme-catalyzed reaction has to be determined.

Concept Introduction:

Certain enzymes require the presence of additional non-protein molecules called cofactors. These may be in the form of metal ions, organometallic compounds or other organic molecules. The enzyme for without its cofactor is termed an apoenzyme. Thus apoenzyme cannot be active unless a cofactor is attached to it.

There are two major categories of cofactors namely the inorganic metal ions and the organic cofactors such as flavin adenine dinucleotide, heme and ${\text{NAD}}^{+}$. The organic cofactor can be further classified into coenzymes and prosthetic groups.