Biochemistry: Concepts and Connections (2nd Edition)
Biochemistry: Concepts and Connections (2nd Edition)
2nd Edition
ISBN: 9780134641621
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
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Chapter 19, Problem 27P
Interpretation Introduction

Interpretation:

Activation of Gemcitabine should be identified.

Concept introduction:

Activation of Gemcitabine indicates the phosphorylation of the drug by an enzyme dCK whereas on eliminating the toxic nature of the drug the deamination of the amino group of the gemcitabine takes place by CDA and thus the drug can be eliminated.

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