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Biology: The Dynamic Science (Mind...

4th Edition
Peter J. Russell + 2 others
ISBN: 9781305389892

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BuyFindarrow_forward

Biology: The Dynamic Science (Mind...

4th Edition
Peter J. Russell + 2 others
ISBN: 9781305389892
Textbook Problem

What is the main reason that searching for open reading frames (ORFs) is more useful for annotating prokaryote protein-coding genes than it is for annotating eukaryote protein-coding genes?

a. Eukaryote protein-coding genes contain introns.

b. The density of protein-coding genes is much higher in eukaryote genomes.

c. In most prokaryotes, all of the protein-coding genes are located on a single circular chromosome.

d. Prokaryotes use a different genetic code than eukaryotes.

e. Prokaryotic protein-coding genes are much longer thaneukaryotic protein-coding genes.

Summary Introduction

Introduction:

Open reading frame (ORF) is a series of codon starting with the initiation codon such as AUG and ending with one of the tree termination codon UAG, UAA, and UGA. The reading frame longer than 100 codons indicate the presence of protein-coding genes. It can be translated into proteins.

Explanation

Justification/explanation for the correct answer:

Option (a) states that eukaryote protein-coding genes contain introns. Open reading frames can be translated into proteins. It does not contain introns. The prokaryotic genome lacks the noncoding region called introns. It is present in the eukaryotic genome. The presence of intron makes the searching of ORF in eukaryotic genome difficult. Since, the introns are absent in prokaryotic genome, searching for open reading frame is possible and is useful for explaining prokaryote protein-coding genes than eukaryotic protein-coding genes. Hence, the option (a) is correct.

The explanation for the incorrect answer

Option (b) states that the density of protein-coding genes is much higher in eukaryotic genomes. Eukaryotes genome is much larger and more complex than prokaryotes genome. The genomes of the eukaryotic cell contain functional genes containing exon and introns. It does not help in explaining the protein-coding genes of a prokaryotic genome. So, it is an incorrect option.

Option (c) states that in most prokaryotes, all of the protein-coding genes are located on a single circular chromosome...

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