Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
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Chapter 2, Problem 29P
In the fruit fly Drosophila melanogaster, the following genes and mutations are known:
Wing size: recessive allele for tiny wings t; dominant allele for normal wings T.
Eye shape: recessive allele for narrow eyes n; dominant allele for normal (oval) eyes N.
For each of the four following crosses, give the genotypes of each of the parents.
| Male | Female | |||||
| Wings | Eyes | Wings | Eyes | Offspring | ||
| 1 | Tiny | Oval | X | Tiny | Oval | 78 tiny wings, oval eyes |
| 24 tiny wings, narrow eyes | ||||||
| 2 | Normal | Narrow | X | Tiny | Oval | 45 normal wings, oval eyes |
| 40 normal wings narrow eyes | ||||||
| 38 tiny wings, oval eyes | ||||||
| 44 tiny wings narrow eyes | ||||||
| 3 | Normal | Narrow | X | Normal | Oval | 35normal wings oval eyes |
| 29 normal wings, narrow eyes | ||||||
| 10 tiny wings, oval eyes | ||||||
| 11 tiny wings, narrow eyes | ||||||
| 4 | Normal | Narrow | X | Normal | Oval | 62 normal wings, oval eyes |
| 19 tiny wings, oval eyes | ||||||
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In Drosophila, the following genes and mutations are known:
Wing size – recessive allele for tiny wings – t; dominant allele for normal wings – T
Eye shape – recessive allele for narrow eyes – d; dominant allele for normal (oval) eyes – D
Eye color – recessive allele for white eyes – r; dominant allele for normal (red) eyes – R
The following cross is performed and the offspring analyzed – TtDdRr X Ttddrr. Give the probabilities for generating the following offspring
a. Flies with at least two recessive traits - Write your answer as a reduced fraction - e.g. 1/8
b. A trihybrid cross is now performed and the offspring analyzed. What is the probability of getting abnormal flies except for the eye shape which will be normal - Write your answer as a reduced fraction - e.g. 1/8
In Drosophila, a cross was made between a yellow-bodied male with vestigial wings and a wild-type (WT) female(brown body and normal wings). The F1 generation consisted of WT males and WT females. The F1 males and females were crossed, and the F2 progeny consisted of 16 yellow males with vestigial wings, 48 yellow males with WT wings, 15 brown males with vestigial wings, 49 WT males, 31 brown females with vestigial wings, and 97 WT females. Based on these results, explain the inheritance of the two genes (i.e. autosomal or sex-linked, dominant or recessive).
Miniature wings (Xm) in Drosophila result from an X-linked allele that is recessive to the allele for long wings (X +). Give the genotypes of the parents in each of the following crosses. Male parent Female parent Male offspring Female offspring a. long long 231 long, 250 miniature 560 long 250 miniature b. miniature long 610 long 632 long c. miniature long 410 long, 417 miniature 412 long, 415 miniature 417 miniature 415 miniature d. long miniature 753 miniature 761 long e. long long 625 long 630 long
Chapter 2 Solutions
Genetics: From Genes to Genomes
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