ESSENTIALS OF GENETICS MCC BUNDLE >BI<
ESSENTIALS OF GENETICS MCC BUNDLE >BI<
9th Edition
ISBN: 9781323915370
Author: KLUG
Publisher: PEARSON
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Chapter 2, Problem 2CS

CASE STUDY | Timing is everything

A man in his early 20s received chemotherapy and radiotherapy as treatment every 60 days for Hodgkin disease. After unsuccessful attempts to have children, he had his sperm examined at a fertility clinic, upon which multiple chromosomal irregularities were discovered. When examined within 5 days of a treatment, extra chromosomes were often present or one or more chromosomes were completely absent. However, such irregularities were not observed at day 38 or thereafter.

Do you think that exposure to chemotherapy and radiotherapy of a spermatogonium would cause more problems than exposure to a secondary spermatocyte?

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6. A 12 year old girl has mental retardation, ataxia, and a history of seizures. She does not speak but engages in frequent and excessive laughter. Cytogenetic analysis shows a deletion involving 15[del(15)(q11;q13). Genetic analysis in this patients family and in several other families with same syndrome shows that affected family members uniformly inherit the chromosome 15 with deletion from their mothers(rather than from their fathers). Tjis phenomenon is best explained by which of the following mechanisms? (A) codominance (B) Fragile sites (C) Genomic imprinting (D) Mitochondrial inheritance (E) X-linked inheritance
1. A recently discovered bird species was found to have 29 chromosomes in its somatic cells before S phase. a. How many chromosomes (2n) are present in a somatic cell during mitosis? b. How many chromosomes does a bird receive from one parent? c. How many sister chromatids are present during metaphase 2? d. Assuming this species follows the same XX/XY sex differentiation as mammals, how many sex chromosomes are in an unfertilized egg? e. How many pairs of homologous chromosomes would you expect to see lined up during metaphase 2? 2. An onion cell (2n) with 10 autosomes and 2 sex chromosomes is about to undergo meiosis. How many cells will result from this process, and what is the chromosome number and ploidy of each cell?  3. An animal is heterozygous for two autosomal genetic traits found on different chromosomes. Purple fur is inherited dominantly (with pp genotype giving green fur) and the gene is located near the telomere on the short arm of an acrocentric autosome. The gene for…
Background Info Rainbow trout go through a unique genetic reproductive process. Female eggs are diploid, while male sperm are haploid. In the wild, when the sperm fertilizes an egg, the extra set of chromosomes is kicked out, resulting in a diploid offspring.Triploid trout are produced in the lab to provide sterile fish stock for lakes. Shortly after the eggs are fertilized, scientists place them in a warm water bath to prevent the extra chromosomes from being removed. The result is a triploid fish that cannot reproduce.Rainbow Trout: n = 30 Global warming is an issue affecting many species around the world. Warming has caused the temperatures in lakes and rivers to increase and stay elevated for longer periods of time. Question Select the FOUR numbers that describe the possible effects of global warming on the reproduction of rainbow trout in the wild and on biodiversity. The extra set of chromosomes remains. The extra set of chromosomes is removed. The offspring are diploid (2n).…

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ESSENTIALS OF GENETICS MCC BUNDLE >BI<

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