Activated-protein-C (APC) resistance is a serum marker that has been associated with thrombosis (the formation of blood clots often leading to heart attacks) among adults. A study assessed this risk factor among adolescents. To assess the reproducibility of the assay, a split-sample technique was used in which a blood sample was provided by 10 people; each sample was split into two aliquots (sub-samples), and each aliquot was assessed separately. Table 2.19 gives the results.
Table 2.19 APC resistance split-samples data
To assess the variability of the assay, the investigators need to compute the coefficient of variation. Compute the coefficient of variation (CV) for each subject by obtaining the
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- A study was undertaken to investigate the effectiveness of an aquarobic exercise program for patients with osteoarthritis. A convenience sample of 70 individuals with arthritis was selected, and each person was randomly assigned to one of two groups. The first group participated in a weekly aquarobic exercise program for 8 weeks; the second group served as a control. Several pieces of data were collected from the individuals, including their total cholesterol (mg). Determine if there is a significant difference in the mean cholesterol for the two groups (aquarobic & control) at the start of the study using a significance level of 0.01. Difference Sample Diff. Std. Error df Aquarobic - Control -13.9045 6.8214 67.8635 What hypotheses should be tested? Make sure to select the hypotheses which are written with notation consistent with the type of samples selected. Ho:μd=0Ho:μd=0Ha:μd>0Ha:μd>0 Ho:μd=0Ho:μd=0Ha:μd<0Ha:μd<0 Ho:μ1=μ2Ho:μ1=μ2Ha:μ1<μ2Ha:μ1<μ2…arrow_forwardThe Paleo diet allows only for foods that humans typically consumed over the last 2.5 million years, excluding those agriculture-type foods that arose during the last 10,000 years or so. Researchers randomly divided 500 volunteers into two equal-sized groups. One group spent 6 months on the Paleo diet. The other group received a pamphlet about controlling portion sizes. A randomized treatment assignment was performed, and at the beginning of the study, the average difference in weights between the two groups was about 0 pounds. After the study, the Paleo group had lost an average of 7.1 pounds with a standard deviation of 22.75 pounds while the control group had lost an average of 4.5 pounds with a standard deviation of 11.5 pounds. After failing to reject the null hypothesis support your answer with a p-value (a) P-value = _______arrow_forwardThe Paleo diet allows only for foods that humans typically consumed over the last 2.5 million years, excluding those agriculture-type foods that arose during the last 10,000 years or so. Researchers randomly divided 500 volunteers into two equal-sized groups. One group spent 6 months on the Paleo diet. The other group received a pamphlet about controlling portion sizes. A randomized treatment assignment was performed, and at the beginning of the study, the average difference in weights between the two groups was about 0 pounds. After the study, the Paleo group had lost an average of 6.5 pounds with a standard deviation of 22.75 pounds while the control group had lost an average of 5.2 pounds with a standard deviation of 10.25 pounds. 95% Confidence Interval ( -1.808, 4.408 ) What is the P-Value? _______arrow_forward
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