Biochemistry: The Molecular Basis of Life
Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 2, Problem 3Q
Summary Introduction

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The estimate of the average mass of a mitochondrion, considering the fact that mitochondria occupy 20% of the volume in the human body and there are 1 × 1016 mitochondria in the body of an adult weighing 70kg.

Introduction:

The mitochondria aredouble-membraned cell organelles, which act as the main site for the aerobic metabolism of the body. These organelles are also involved in various metabolic processes such as the β-oxidation of fatty acids. The mitochondria have a naked deoxyribonucleic acid (DNA) and the number of mitochondria in a cell depends on its function.

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It has been estimated that mitochondria occupy 20% of the volume in the human body. For a 70- kg adult, the average number of mitochondria has been estimated to be 1 × 10 (10,000 trillion). Using this information, provide a rough estimate of the average mass of a mitochondrion.
Describe in general terms the structural makeup of a mitochondrion.
Imagine that you develop a procedure to measure the pH of in the matrix and the intermembrane space of a mitochondrion. What pattern of pH would you see?     The pH in the intermembrane space will contain more H+ and have a lower pH compared to the matrix.     The pH in the intermembrane space will contain more H+ and have a higher pH compared to the matrix.     The pH within the matrix will contain more H+ and have a lower pH compared to the intermembrane space.     The pH within the matrix will contain more H+ and have a higher pH compared to the intermembrane space.
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