ESSENTIALS OF GENETICS-W/MOD.ACCESS
9th Edition
ISBN: 9780134452876
Author: KLUG
Publisher: PEARSON
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Chapter 20, Problem 13PDQ
The Drosophila homeotic mutation spineless aristapedia (ssa) results in the formation of a miniature tarsal structure (normally part of the leg) on the end of the antenna. What insight is provided by (ssa) concerning the role of genes during determination?
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Chapter 20 Solutions
ESSENTIALS OF GENETICS-W/MOD.ACCESS
Ch. 20 -
CASE STUDY |One foot or another
In humans the...Ch. 20 - CASE STUDY| One foot or another In humans the HOXD...Ch. 20 - CASE STUDY| One foot or another In humans the HOXD...Ch. 20 - HOW DO WE KNOW? In this chapter, we have focused...Ch. 20 - Review the Chapter Concepts list on page 403. Most...Ch. 20 -
3. Nuclei from almost any source may be injected...Ch. 20 -
4. Distinguish between the syncytial blastoderm...Ch. 20 - (a) What are maternal-effect genes? (b) When are...Ch. 20 - (a) What are zygotic genes, and when are their...Ch. 20 - List the main classes of zygotic genes. What is...
Ch. 20 -
8. Experiments have shown that any nuclei placed...Ch. 20 - How can you determine whether a particular gene is...Ch. 20 -
10. You observe that a particular gene is being...Ch. 20 - What are Hox genes? What properties do they have...Ch. 20 -
12. The homeotic mutation Antennapedia causes...Ch. 20 - The Drosophila homeotic mutation spineless...Ch. 20 - A number of genes that control expression of Hox...Ch. 20 - In Arabidopsis, flower development is controlled...Ch. 20 - Prob. 16PDQCh. 20 - Dominguez et al. (2004) suggest that by studying...
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- Most organisms display a circadian rhythm, a cycling of biological processes that is roughly synchronized with day length. In Drosophila, pupae eclose (emerge as adults after metamorphosis) at dawn. a)Using this knowledge how would screen for Drosophila mutants that have an impaired circadian rhythm? b)In each case, how would you clone the genes you identified by mutation?arrow_forwardDiscuss the morphological differences between the parasegments and segments of Drosophila. Discuss the evidence, providing specific examples, that suggests the parasegments of the embryo are the subdivisions for the organization of gene expression.arrow_forwardWhat would be the most likely effect of inhibiting the translation of hunchback mRNA throughout a Drosophila embryo?arrow_forward
- . Let’s say that you have incredible skill and can isolate the white and red patches of tissue from the Drosophila eyes shown in Figure 12-24 in order to isolate mRNA from each tissue preparation. Using your knowledge of DNA techniques from Chapter 10, design an experiment that would allow you to determine whether RNA is transcribed from the white gene in the red tissue or the whitetissue or both. If you need it, you have access to radioactive white-gene DNAarrow_forwardA strain of Arabidopsis thaliana possesses a mutation in the APETALA2 gene. As a result of this mutation, much of the 3′ UTR of the mRNA transcribed from the gene is deleted. What is the most likely effect of this mutation on the expression of the APETALA2 gene?arrow_forwardResearchers have identified a gene in humans that (when mutated) causes tremors and unstable walking due to neurological problems. This disorder is inherited in an autosomal recessive manner, and the mutant allele isknown to result from a loss-of-function mutation. The same gene hasbeen found in mice, although a mutant mouse version has not beendiscovered. To develop an effective drug therapy to treat this disorderin humans, it would be experimentally useful to have a mouse model.In other words, it would be desirable to develop a strain of mice thatcarry the mutant allele in the homozygous condition. How would youdevelop such a strain?arrow_forward
- Discuss the similarities and differences between the bithorax and Antennapedia complexes in Drosophila and the Hox gene complexes in mice.arrow_forwardWhat is the signaling pathway that mediates the organizing activity of the A/P organizer in the Drosophila wing disc? Describe two experiments that suggest this pathway functions to organize pattern and promote growth along the anterior/posterior axis of wing imaginal discs.arrow_forwarda. The eyeless gene is required for eye formation in Drosophila. It encodes a homeodomain. What would you predict about the biochemical function of the Eyeless protein?b. Where would you predict that the eyeless gene is expressed in development? How would you test your prediction? c. The Small eye and Aniridia genes of mice and humans, respectively, encode proteins with very strong sequence similarity to the fly Eyeless protein, and they are named for their effects on eye development. Devise one test to examine whether the mouse and human genes are functionally equivalent to the fly eyeless gene.arrow_forward
- Can I get a paragraph about the Repo protein that is used in Drosophila melangaster?arrow_forwardGunter Korge examined several proteins that are secreted from the salivary glands of Drosophila melanogaster during larval development (G. Korge. 1975. Proceedings of the National Academy of Sciences of the United States of America 72:4550–4554). One protein, called protein fraction 4, was encoded by a gene found by deletion mapping to be located on the X chromosome at position 3C. Korge observed that, about 5 hours before the first synthesis of protein fraction 4, an expanded and puffed-out region formed on the X chromosome at position 3C. This chromosome puff disappeared before the end of the third larval instar stage, when the synthesis of protein fraction 4 ceased. He observed that there was no puff at position 3C in a special strain of flies that lacked secretion of protein fraction 4. Explain these results. What is the chromosome puff at region 3, and why does its appearance and disappearance roughly coincide with the secretion of protein fraction 4?arrow_forward
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