To determine: The number of genes that are necessary to specify a complete developmental network for a fruit fly.
Introduction: It is observed that developmental genetics depends on the regulation and expression of a complex network of genes through transcription factors. In Drosophila, such a network is seen to regulate the body plan and the morphological structures of the organism.
To determine: The number of genes that are needed for a network to specify one segment.
Introduction: It is observed that developmental genetics depends on the regulation and expression of a complex network of genes through transcription factors. In Drosophila, such a network is seen to regulate the body plan and the morphological structures of the organism.
Want to see the full answer?
Check out a sample textbook solutionChapter 20 Solutions
BIOLOGY-TEXT
- Explain how loss-of-function mutations in the following categories of genes would affect the morphologies of Drosophila larvae: A. Gap genes B. Pair-rule genes C. Segment-polarity genesarrow_forwardWhy is an understanding of gene regulation in eukaryotes crucial to an understanding of developmental processes? Explain your answerarrow_forwardHow have we discovered that specific genes control development in an organism like Drosophila?arrow_forward
- Another way to study the role of proteins (e.g., transcription factors) that function in development is to microinject the mRNA that encodes a protein, or the purified protein itself, into an oocyte or embryo, and then determine how this affects the subsequent development of the embryo, larva, and adult. For example, if Bicoid protein is injected into the posterior region of an oocyte, the resulting embryo will develop into a larva that has anterior structures at both ends. Based on your understanding of the function of each developmental gene, what would be the predicted phenotype if the following proteins or mRNAs were injected into normal oocytes? A. Nanos mRNA injected into the anterior end of an oocyte B. Antp protein injected into the posterior end of an embryo C. Toll mRNA injected into the dorsal side of an early embryoarrow_forwardDiscuss the role of homeotic genes in development. Explain what happens to the phenotype of a fruit fly when a gain-of-function mutation in a homeotic gene causes the protein to be expressed in an abnormal region of the embryo. What are the consequences of a loss-of-function mutation in such a gene?arrow_forwardDescribe the role of coordinate genes, gap genes, pair rule genes, segment polarity genes, and homeotic genes in Drosophila development.arrow_forward
- In plants, floral organs develop from concentric rings of tissue called whorls. Beginning from the most outside ring, whorl 1 develops into sepals, whorl 2 develops into petals, whorl 3 develops into stamens, and whorl 4 develops into carpels. Analogous to the homeotic mutants of Drosophila, recessive mutations were found in genes that encode transcription factors. These mutants change the organ identity of a given whorl to the identity of a different whorl. The following table shows the mutant phenotypes caused by various floral organ mutations found in the genetic model plant, Arabidopsis. Genotype wild-type ap2 lap2 ap3 lap3 ag lag sepals carpels sepals sepals whorls 2 and 3 whorls 3 and 4 whorls 1 and 2 whorls 2 and 4 All four whorls 1 petals stamens sepals petals Based on the table above, which whorls require a functional AG gene. 2 Whorl stamens stamens carpels petals 3 carpels carpels carpels sepals 4arrow_forwardPax6 is a gene that is involved in mammalian eye development. Mutations in this gene result in a lack of iris in humans, and mice that are homozygous for the mutation lack eyes completely. Mutations in the eyeless gene in the fruitfly Drosophila result in reduced eyes. Expressing Pax6 from mammals in other tissues of Drosophila during its embryonic development can result in an ectopic eye (e.g. an eye expressed in a different tissue type). An example of an ectopic eye on the antenna of Drosophila is shown below. Part A: The eye of humans, mouse, and fly are an example of the following (check all that apply) A. Structural analog B. Structural homolog C. Developmental homolog D. Genetic homolog Part B: Darwin's hypothesis of natural selection has two components: Species are not static but change through time Species are related, and not independent. In what ways does the human, mouse, and fly eye support or contradict one or both of the two components of…arrow_forwardWhat would be the most likely result of injecting bicoid mRNA into the posterior end of a Drosophila embryo and inhibiting the translation of nanos mRNA?arrow_forward
- You isolate a glp-1 mutation of C. elegans and discover that the DNA region encoding the spatial control region (SCR) has been deleted. What will the GLP-1 protein expression pattern be in a four-cell embryo in mutant heterozygotes? In mutant homozygotes?arrow_forwardDescribe the formation steps of the primary axis that first occurs during development in Drosophila by explaining each molecule.arrow_forwardA number of genes that control expression of Hox genes in Drosophila have been identified. One of these homozygous mutants is extra sex combs, where some of the head and all of the thorax and abdominal segments develop as the last abdominal segment. In other words, all affected segments develop as posterior segments. What does this phenotype tell you about which set of Hox genes is controlled by the extra sex combs gene?arrow_forward
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education