Human Anatomy & Physiology (2nd Edition)
2nd Edition
ISBN: 9780134553511
Author: Erin C. Amerman
Publisher: PEARSON
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Chapter 20, Problem 20CYR
Summary Introduction
Introduction:
Autoimmunity is the condition when an immune response is generated against self-antigens present in the body. This results in the autoimmune disorder, which may be localized or systemic, depending upon the number of organs affected. Such disorders result in type II, III or IV hypersensitivity and result in damage to tissues and organs. There are several conditions that can result in the development of autoimmunity.
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Which of the following statements is not true?(A) An antibody has more than one antigen-binding site.(B) A lymphocyte has receptors for multiple differentantigens.(C) An antigen can have different epitopes.(D) A liver or muscle cell makes one class of MHC molecule.
Which of the following best describes the impacts of antigenic variation? Mark all that apply.
A. requires clonal selection of B cells
B. causes a primary immune response
C. involves T-independent immune responses
D. memory cells are stimulated by the antigen variants
Which of the following statements regarding T cells activated by specific antigen is incorrect?
a. They receive co-stimulatory signals through CD28.
b. They suppress expression of sphingosine 1-phosphate (SIP).
c. They take several days before differentiating into effector T cells.
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e. They begin to express CTLA4, which serves to limit T-cell proliferation.
Chapter 20 Solutions
Human Anatomy & Physiology (2nd Edition)
Ch. 20.1 - What are the main functions of the lymphatic...Ch. 20.1 - 2. How do lymphatic capillaries differ from blood...Ch. 20.1 - What is the pathway of lymph flow from the right...Ch. 20.1 - 4. What main cell types are located in lymphoid...Ch. 20.1 - List the main functions of MALT, lymph nodes, the...Ch. 20.2 - 1. How do innate immunity and adaptive immunity...Ch. 20.2 - 2. What are the three lines of defense?
Ch. 20.2 - What are the bodys main surface barriers, and how...Ch. 20.2 - Prob. 4QCCh. 20.2 - How are the immune system and lymphatic system...
Ch. 20.3 - Match the following cell types with their correct...Ch. 20.3 - Which of the cells in question 1 do not directly...Ch. 20.3 - What is the complement system, and what are its...Ch. 20.3 - In what two ways is the complement system...Ch. 20.3 - 5. What are the main cytokines of innate...Ch. 20.3 - What are the four cardinal signs of inflammation?Ch. 20.3 - 7. What are inflammatory mediators, and what do...Ch. 20.3 - Explain the role of phagocytes in the inflammatory...Ch. 20.3 - What causes the elevated temperature and common...Ch. 20.3 - Prob. 10QCCh. 20.4 - 1. What are MHC molecules?
Ch. 20.4 - 2. How do class I and class II MHC molecules...Ch. 20.4 - How are T cells activated?Ch. 20.4 - Prob. 4QCCh. 20.4 - What are the main functions of TC cells?Ch. 20.4 - Prob. 6QCCh. 20.4 - Prob. 7QCCh. 20.5 - 1. How is a B cell activated?
Ch. 20.5 - Prob. 2QCCh. 20.5 - What are the five classes of antibody, and how do...Ch. 20.5 - 4. List the five main functions of antibodies.
Ch. 20.5 - How do the primary and secondary immune responses...Ch. 20.5 - 6. What is the purpose of a vaccination, and what...Ch. 20.5 - 7. How do active immunity and passive immunity...Ch. 20.6 - How do innate immunity and adaptive immunity work...Ch. 20.6 - Walk through the basic steps of the immune...Ch. 20.6 - How does the immune system survey the body for...Ch. 20.6 - Walk through the steps of the immune response to...Ch. 20.6 - Prob. 5QCCh. 20.6 - 6. How do cancer cells escape the immune response...Ch. 20.7 - Define the four types of hypersensitivity...Ch. 20.7 - Explain how type IV hypersensitivity differs from...Ch. 20.7 - How do primary and secondary immunodeficiency...Ch. 20.7 - Prob. 4QCCh. 20.7 - What is an autoimmune disorder? What produces the...Ch. 20.7 - 6. What are the potential causes of autoimmune...Ch. 20 - 1. Which of the following is not a function of the...Ch. 20 - Mark the following statements as true or false. If...Ch. 20 - Fill in the blanks: The lymphoid organ that...Ch. 20 - Fill in the blanks: Nonspecific immunity is also...Ch. 20 -
5. Which of the following make up the body’s...Ch. 20 - Which of the following does not describe the...Ch. 20 - Mark the following statements as true or false. If...Ch. 20 - Which of the following functions is/are performed...Ch. 20 - Prob. 9CYRCh. 20 - 10. When naïve B cells are activated, they...Ch. 20 - 11. Match the following antibodies with the...Ch. 20 - Mark the following statements as true or false. If...Ch. 20 - Prob. 13CYRCh. 20 - On which type(s) of cells are class I MHC...Ch. 20 - Fill in the blanks: Class I MHC molecules display...Ch. 20 - 16. Which of the following is not a role of TH...Ch. 20 - 17. Mark the following statements as true or...Ch. 20 - 18. Type I hypersensitivity is due to release of...Ch. 20 - Prob. 19CYRCh. 20 - Prob. 20CYRCh. 20 - Prob. 1CYUCh. 20 - Complement proteins are crucial for stimulating...Ch. 20 - 3. Terrence has severe asthma and allergies, and...Ch. 20 - Your friend tests her snake-wrangling skills on an...Ch. 20 - 2. Carla presents to her physician with a...Ch. 20 - 3. Mr. White has been diagnosed with febrile...Ch. 20 - Mr. White developed neutropenia as a consequence...Ch. 20 - 5. The chemotherapeutic drugs Mr. White is taking...
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Similar questions
- Which of the following pairs is mismatched? a. plasma cell: mediation of phagocytosis and killing of microorganisms in the plasma b. megakaryocyte: formation of platelets c. dendritic cell: activation of adaptive immune responses d. natural killer cell: develops from a common lymphoid progenitor e. neutrophil: formation of pus f. regulatory T cell: inhibition of T-cell activity.arrow_forwardWhich of the following can serve as antigen-presenting cells (APCs)?a. T cells b. B cells c. macrophages d. dendritic cells e. b, c, and darrow_forwardWhich of the following does not occur during a secondary immuneresponse?a. Antibodies are made quickly and in great amounts.b. Antibody production lasts longer than in a primary response.c. Clonal selection occurs for B cells.d. All of these are correct.arrow_forward
- Receptors that trigger innate immune responses a. are antibodies recognizing specific antigens. b. are T-cell receptors recognizing specific antigens. c. recognize pathogen-associated molecular patterns. d. are not specific at all.arrow_forwardWhich of the following statements is NOT true of a fever?a. Temperature is regulated by chemicals that reset the body's thermostat to a higher setting.b. The higher than normal body temperature impairs the functions of some bacteria.c. The higher than normal body temperature is always harmful.d. The higher temperature impairs leukocytes andantibody production.e. Both c and d. Which of the following statements is NOT true of antibodies?a. They bind to foreign antigens, making them susceptible to being engulfed by phagocytes.b. They serve as specific binding sites on B cells.c. An antibody is usually able to bind to a variety of different types of antigensd. They are composed of two heavy chains and two light chains.arrow_forwardAntibodies against a specific antigen can be injected into a person to provide passive immunity. For which reason is this NOT as effective as the process of vaccination with that antigen? Select one: a. Injection of antibodies may cause allergic reactions, while vaccination never causes allergic reactions. b. Injection of antibodies does not provide long-lasting immunity, and vaccination with antigens triggers a clonal selection of B cells and cytotoxic T cells. c. Vaccination with antigens triggers a clonal selection of B cells and cytotoxic T cells. d. Injection of antibodies does not provide long-lasting immunity. e. Injection of antibodies does not provide long-lasting immunity and may cause allergic reactions, while vaccination never causes allergic reactions.arrow_forward
- Activated helper T Cells participate in which of the following processes? a.) Differentiation of memory B cells b.) Activation of cytotoxic T Cells c.) Facilitation of macrophage phagocytosis d.) All of abovearrow_forwardExplain why each choice (a-d) is correct or incorrect. T cells are differentiated into two groups based on their glycoproteins CD4 or CD8. Which of the following is true of CD4 T cells? a. They become cytotoxic T cells. b. The become antigen presenting cells. c. They become T helper cells. d. They become plasma cells.arrow_forwardWhich of the following is part of the second line of defense against pathogens?a. skin b. mucus membranesc. lysozyme in tears d. phagocytes Which of the following does NOT have MHC class II molecules on the surface of their cell membranes? a. Macrophages.b. Dendritic cells.c. B cells.d. Helper T cells.arrow_forward
- Which of the following is NOT true about T cells?(a) T cells develop from lymphoid stem cells in the bonemarrow and mature in the thymus.(b) Cell-mediated immunity is primarily carried out by Tcells.(c) Subsequent differentiation of T cells produces cytotoxic(killer) T cells, delayed-hypersensitivity T cells, helper Tcells, and regulatory T cells.(d) Natural killer cells (NK) are exclusively differentiated Tcells.(e) T cells act in situations where antigens are embeddedin cell membranes or are inside host cells and thus areinaccessible to antibodies.arrow_forwardExplain why each choice (a-d) is correct or incorrect. A vaccine is effective because a. The vaccine contains the antibodies necessary to fight infection. b. The vaccine contains the lymphocytes necessary to fight infection. c. The secondary response of the adaptive immunity is faster and more efficient than the primary response. d. B lymphocytes are unable to mount an immune response the first time they are exposed to a new pathogen.arrow_forwardIbuprofen dampens the immune system’s inflammation response.What might be a short-term consequence of taking ibuprofen?a. Blood vessels may become less permeable.b. Antibodies may become less active.c. Cytotoxic T cells may begin to divide.d. All of the above are correctarrow_forward
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