GENETICS:ANALYSIS+PRIN.(LL)-W/ACCESS
GENETICS:ANALYSIS+PRIN.(LL)-W/ACCESS
6th Edition
ISBN: 9781260239775
Author: BROOKER
Publisher: MCG
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Chapter 20, Problem 2EQ

The work of McClintock showed that the presence of a transposon can create a mutable site or locus that is subject to frequent chromosome breakage. Why do you think a transposon creates a mutable site? If chromosome breakage occurs, do you think the transposon has moved somewhere else? How would you experimentally determine if it has?

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Colchicine is a chemical mutagen that inhibits the spindle formation and prevents anaphase, which retains the cell’s single restitution nucleus (doubled chromosome number). Suppose that an onion (2n=16) is subjected to three consecutive rounds of colchicine treatment, what will be the resulting chromosome number of the treated onion?
In each of the illustrations below, a segment of a chromosome has two copies of a transposable element. In panel a, they are oriented in the same direction, whereas in panel b they are in opposite directions. A double strand break occurs in element A and is repaired by homologous recombination using element B as a repair template. For each case, what will the chromosome look like after homologous recombination occurs? Choose one of the five options below, 1-5.
A reciprocal translocation occurs in an individual between chromosomes 4 and 18, and this translocation causes a disease in the individual. What is the most likely reason chromosome mutation causes a disease? a) The translocation causes a break in the chromosome in a gene regulatory region. b) Chromosomes with a translocation cannot replicate. c) An individual with a translocation has some genes duplicated. d) An individual with a translocation has some genes missing.

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GENETICS:ANALYSIS+PRIN.(LL)-W/ACCESS

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