ND STONY BROOK UNIVERSITY LOOSELEAF GENETICS: FROM GENES TO GENOMES
6th Edition
ISBN: 9781260406092
Author: HARTWELL, Leland, HOOD, Leroy, Goldberg, Michael
Publisher: Mcgraw-hill Education/stony Brook University
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Chapter 20, Problem 3P
Summary Introduction
To determine:
The role of dietary habits and genetic differences in the development of colon cancer.
Introduction:
The colon is a part of the large intestine. It is present at the lower end of the intestine. Cancer is defined as the abnormal growth of cells. Any abnormal malignant growth of cells in colon or rectum is termed as colon cancer.
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A survey of Canadian males was performed in during the 1980s. 52% of adult males smoked. The lifetime probability of getting lung cancer in male smokers was 17.2% compared to 1.3% in non-smoking males.
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What is the probability that he smoked?
Pr[smoke | cancer] = ?
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In a study, where the causal relationship between alcohol drinking and colon cancer was studied, there were 2000 people who consume alcohol and there were 2000 people who do not consume alcohol. These populations were followed up for 10 years and after the following period there were 280 people who had colon cancer in alcohol drinker group, compared with 100 people having colon cancer in the non-drinker group.
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A survey of Canadian adult males was performed during the 1980s. 52% of the respondents smoked. The lifetime probability of a smoker getting lung cancer was 17.2%, whereas a non-smoker had a cancer probability of 1.3%.
a)What is the conditional probability of a male smoker getting lung cancer?
b)Draw a probability tree showing the probability of getting lung cancer conditional on smoking or not smoking.
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d)Show the same calculation as c), but in the format of the general multiplication rule Pr[A and B] = Pr[A] Pr[B|A]
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Chapter 20 Solutions
ND STONY BROOK UNIVERSITY LOOSELEAF GENETICS: FROM GENES TO GENOMES
Ch. 20 - For each of the terms in the left column, choose...Ch. 20 - Characterize the differences between tumor cells...Ch. 20 - Prob. 3PCh. 20 - Prob. 4PCh. 20 - A carcinogenic compound is placed on the skin of...Ch. 20 - You have decided to study genetic factors...Ch. 20 - B cells are specialized blood cells that secrete...Ch. 20 - Molecules outside and inside the cell regulate the...Ch. 20 - Put the following steps in the correct ordered...Ch. 20 - a. Would you expect a cell to continue or to stop...
Ch. 20 - Two different protein complexes called SCF and APC...Ch. 20 - One of the hallmarks of mitotic anaphase is the...Ch. 20 - Concerning the Tools of Genetics Box Analysis of...Ch. 20 - Are genome and karyotype instabilities...Ch. 20 - Prob. 15PCh. 20 - Why dont all loss-of-function mutations that are...Ch. 20 - Chromothripsis is a rare phenomenon, first...Ch. 20 - The chromosome 9/22 translocation associated with...Ch. 20 - A female patient 19 years old, whose symptoms are...Ch. 20 - Prob. 20PCh. 20 - A generic signaling cascade is shown in the...Ch. 20 - Neurofibromatosis type 1 NF1; also known as von...Ch. 20 - Families with germ-line BRCA1 or BRCA2...Ch. 20 - The text explained that retroviruses can cause...Ch. 20 - Hepatocellular carcinoma is the most frequent form...Ch. 20 - Suppose that instead of microarrays, you analyzed...Ch. 20 - Prob. 27PCh. 20 - Glioblastoma multiforme GBM is the most common and...Ch. 20 - a. The legend to Fig. 20.29 identifies which of...Ch. 20 - The website CBioPortal http://www.cbioportal.org...
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