HUMAN BIOLOGY
16th Edition
ISBN: 9781260233032
Author: Mader
Publisher: RENT MCG
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Chapter 20.1, Problem 2CYP
Describe how mutations in tumor suppressor genes and proto-oncogenes regulate the cell cycle.
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Describe how the tumor-suppressor genes Rb, p53 and p21 regulate the cell cycle.
Describe how tumor suppressors function to stop the cell cycle until certain events are completed
Explain why mutations in tumor suppressor genes are recessive (both copies of the gene must be defective for the regulation of cell division to be defective), whereas mutations in oncogenes are dominant.
Chapter 20 Solutions
HUMAN BIOLOGY
Ch. 20.1 - Descrihe the characteristics of cancer cells that...Ch. 20.1 - Prob. 2LOCh. 20.1 - Prob. 3LOCh. 20.1 - Prob. 1BTSCh. 20.1 - Prob. 2BTSCh. 20.1 - List the characteristics of cancer cells that...Ch. 20.1 - Describe how mutations in tumor suppressor genes...Ch. 20.1 - Prob. 3CYPCh. 20.2 - Prob. 1LOCh. 20.2 - Prob. 2LO
Ch. 20.2 - Summarize how protective behaviors and diet can...Ch. 20.2 - Prob. 1BTHCh. 20.2 - Prob. 2BTHCh. 20.2 - Prob. 1CYPCh. 20.2 - List the environmental carcinogens that are known...Ch. 20.2 - Prob. 3CYPCh. 20.3 - Prob. 1LOCh. 20.3 - Prob. 2LOCh. 20.3 - Prob. 1CYPCh. 20.3 - Identify the routine screening tests that are...Ch. 20.3 - Prob. 3CYPCh. 20.4 - Prob. 1LOCh. 20.4 - Prob. 2LOCh. 20.4 - Describe the three types of therapy that are...Ch. 20.4 - Discuss why cancer treatment may involve a...Ch. 20.4 - Prob. 3CYPCh. 20 - Prob. 1ACh. 20 - Prob. 2ACh. 20 - Angiogenesis stimulates the development of new...Ch. 20 - Prob. 4ACh. 20 - 5. Concerning the causes of cancer, which one is...Ch. 20 - Prob. 6ACh. 20 - Prob. 7ACh. 20 - Prob. 8ACh. 20 - Prob. 9ACh. 20 - Prob. 10ACh. 20 - Prob. 1TCCh. 20 - Prob. 2TCCh. 20 - Prob. 3TCCh. 20 - Prob. 4TCCh. 20 - Prob. 5TC
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- How can errors in the cell cycle lead to cancer in humans?arrow_forwardA gene that codes for a positive cell cycle regulator is called a(n) _______. a. kinase inhibitor b. tumor suppressor gene c. proto-oncogene d. oncogenearrow_forwardAnother model, the random model, proposes that any cell in a malignant tumor has the potential to form a new tumor. Does the cancer stem cell hypothesis contradict this idea?arrow_forward
- Figure 10.13 Rb and other proteins that negatively regulate the cell cycle are sometimes called tumor suppressors. Why do you think the name tumor suppressor might be appropriate for these proteins?arrow_forwardApart from p53, mention and describe the function of three tumor suppressor genes you knowarrow_forwardExplain the normal regulation of proto-oncogenes and tumor suppressor genes that prevents cells from becoming cancerous.arrow_forward
- describe how mutations in proto-oncogenes and tumor suppressor genes cause most types of cancerarrow_forwardExplain how mutations in tumor-suppressor genes can be recessive at the level of the cell but cause dominantly inherited predispositions to cancer.arrow_forwardDescribe how is cancer related to cell cyclearrow_forward
- Describe cancer cell types and the differentiation process that occurs during cancer development.arrow_forwardDescribe the steps by which the TP53 gene responds to DNA damage and/or cellular stress to promote cell-cycle arrest and apoptosis. Given that TP53 is a recessive gene and is not located on the X chromosome, why would people who inherit just one mutant copy of a recessive tumor-suppressor gene be at higher risk of developing cancer than those without the recessive gene?arrow_forwardDescribe the relationship between cell cycle and link to cancer. Use the following terms in your explanation: tumor, oncogene, tumor suppressor, apoptosis.arrow_forward
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