(a)
Interpretation:
The reagent has to be proposed for the conversion of A to B.
Concept introduction:
Michael reaction:
The nucleophile is reaction with α,β-unsaturated carbonyl compound (1,4 –addtion) which yield the addition product is called Michael reaction.
(b)
Interpretation:
The reagent has to be proposed for the conversion of B to C.
Concept introduction:
Reduction:
(c)
Interpretation:
The reagent has to be proposed for the conversion of C to D.
Concept introduction:
Chlorination: Alcohols reaction with thionyl chloride gives chlorinated compound.
(d)
Interpretation:
The mechanism has to be proposed for the conversion of E to F and the formation of methyl chloride has to be shown through mechanism.
(e)
Interpretation:
The reagent has to be proposed for the conversion of F to Fluoxetine.
Concept introduction:
Hydrolysis: Amide undergoes hydrolysis using base like sodium hydroxide gives acid.
(f)
Interpretation:
The possible stereoisomer’s has to be shown if the product is chiral.
Concept introduction:
Chiral:
A molecule is non superimposable on its mirror image is called chiral molecule.
Four different atoms attached to a carbon atom is called chiral molecule.
Isomer: A molecule having the same molecular formula but with different chemical structure is called isomer.
Stereoisomers: Stereoisomers are molecules that have the same molecular formula and they differ only in arrangement of atom in three-dimensional space.
Enantiomers: A compound which is non-superimposable mirror image is called enantiomers.
Diastereomers: A compound which is non-superimposable and non-mirror image is called diastereomers.
Racemic mixture: A racemic mixture is simply a mixture containing an equal amount of each enantiomer.
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EP ORGANIC CHEMISTRY-OWL V2 ACCESS
- Identify products A and B from the given 1H NMR data. Treatment of acetone [(CH3)2C=O] with dilute aqueous base forms B. Compound B exhibits four singlets in its 1H NMR spectrum at 1.3 (6 H), 2.2 (3 H), 2.5 (2 H), and 3.8 (1H) ppm. What is the structure of B?arrow_forwardWhat reagents would you use to carry out the following reaction? (A) H₂ / Pt (B) (C) (D) H₂/Lindlar's ??? Li, EtNH₂ followed by NH4Cl H₂O₂ / NaOHarrow_forwardDraw a structural formula for the product formed by treating butanal with each reagent. (a) LiA1H4LiA1H4 followed by H2OH2O (b) NaBH4NaBH4 in CH3OH/H2O (c) H2/Pt (d) Ag(NH3)2+in NH3/H2O (e) H2CrO4, heat (f) HOCH2CH2OH,HClarrow_forward
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- Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning