BIOCHEMISTRY (LOOSELEAF)-W/ACCESS
9th Edition
ISBN: 9781319425784
Author: BERG
Publisher: Macmillan Higher Education
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Question
Chapter 21, Problem 30P
Interpretation Introduction
Interpretation:
The complete oxidation of glucose 6-phosphate derived from free glucose yields30 molecules ATP, whereas the complete oxidation of glucose 6- phosphate derived from glycogen yields 31 molecules of ATP , this difference should be accounted.
Concept introduction:
Glycogen is a readily mobilized storage form of glucose. It is a very large, branched
Enzyme phosphoglucomutase breakdown glycogen into glucose 6-phosphate. Catalyzed by the glycogen phosphorylase enzyme.
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How many ATP are produced from a triglyceride containing three 14 carbon fatty acids?
NOTE: Assume that glycerol is converted to Glyceraldehyde-3-Phosphate (step 6 of glycolysis).
The glucose/glucose-6-phosphate substrate cycle involves distinct
reactions of glycolysis and gluconeogenesis that interconvert these
two metabolites. Assume that under physiological conditions,
[ATP] = [ADP]; [P;] = 1 mM.
Consider the glycolytic reaction catalyzed by hexokinase:
ATP + glucose ADP + glucose-6-phosphate
AG = - 16.7 kJ/mol
(a) Calculate the equilibrium constant (K) for this reaction at 298°K,
and from that, calculate the maximum [glucose-6-phosphate]/
Iglucose] ratio that would exist under conditions where the reaction is
still thermodynamically favorable.
(b) Reversal of this interconversion in gluconeogenesis is catalyzed
by glucose-6-phosphatase:
glucose-6-phosphate + H20 = glucose + P
AG" = -13.8 kJ/mol
In which of the following metabolic conversions is ATP “generated” during glycolysis?
Glucose —> Glucose-6-phosphate
1,3-Bisphosphoglycerate —> 3-Phosphoglycerate
Fructose-1,6-bisphosphate —> Dihydroxyacetone phosphate + Glyceraldehyde-3-phosphate
Glucose-6-phosphate —> Fructose-6-phosphate
2-Phosphoglycerate —> 3-Phosphoglycerate
Chapter 21 Solutions
BIOCHEMISTRY (LOOSELEAF)-W/ACCESS
Ch. 21 - Prob. 1PCh. 21 - Prob. 2PCh. 21 - Prob. 3PCh. 21 - Prob. 4PCh. 21 - Prob. 5PCh. 21 - Prob. 6PCh. 21 - Prob. 7PCh. 21 - Prob. 8PCh. 21 - Prob. 9PCh. 21 - Prob. 10P
Ch. 21 - Prob. 11PCh. 21 - Prob. 12PCh. 21 - Prob. 13PCh. 21 - Prob. 14PCh. 21 - Prob. 15PCh. 21 - Prob. 16PCh. 21 - Prob. 17PCh. 21 - Prob. 18PCh. 21 - Prob. 19PCh. 21 - Prob. 20PCh. 21 - Prob. 21PCh. 21 - Prob. 22PCh. 21 - Prob. 23PCh. 21 - Prob. 24PCh. 21 - Prob. 25PCh. 21 - Prob. 26PCh. 21 - Prob. 27PCh. 21 - Prob. 28PCh. 21 - Prob. 29PCh. 21 - Prob. 30PCh. 21 - Prob. 31PCh. 21 - Prob. 32PCh. 21 - Prob. 33PCh. 21 - Prob. 34PCh. 21 - Prob. 35PCh. 21 - Prob. 36PCh. 21 - Prob. 37PCh. 21 - Prob. 38PCh. 21 - Prob. 39PCh. 21 - Prob. 40PCh. 21 - Prob. 41PCh. 21 - Prob. 42PCh. 21 - Prob. 43PCh. 21 - Prob. 44PCh. 21 - Prob. 45PCh. 21 - Prob. 46P
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