Concept explainers
Interpretation:
The reason that supports succinate dehydrogenase is the coenzyme in the reaction of citric acid cycle which is catalyzed by
Concept Introduction:
Citric Acid Cycle: It involves 8 series reaction which converts acetyl group present in acetyl coenzyme A into 2
Coenzyme: They are non-proteins molecules which helps enzymes for catalyzing the reaction.
Flavin Adenine Dinucleotide
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FUND.OF GEN CHEM CHAP 1-13 W/ACCESS
- Based on your knowledge of the structure of NAD+ and an assumption that coenzyme dissociation is the rate limiting step of the alcohol dehydrogenase mechanism, hypothesize why a N249W mutation at the coenzyme binding site would increase the rate of catalysis.arrow_forwardBoth prokaryotic and eukaryotic organisms carry out some form of glycolysis. How does ha fact support or not support the assertion that glycolysis is one of the oldest metabolic pathways?arrow_forwardWhat would happen to the citric acid cycle if NADH and FADH2 were not reoxidized?arrow_forward
- What enzymes from the citric acid cycle that are allosterically regulated by ATP and/or NADH? What enzymes from the citric acid cycle that allosterically regulated by NAD+?arrow_forwardHow many NADH and how many FADH2 molecules are formed in the citric acid cycle?arrow_forwardWhich reaction in the citric acid cycle is most analogous to the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate? What kind of enzymebound intermediate is formed in both reactions?arrow_forward
- The citric acid cycle operates only when O2 is present, yet O2 is not a substrate for the cycle. Explain.arrow_forwardWhich of the enzymes in glycolysis are NADH linked dehydrogenases?arrow_forwardWhy is the Krebs cycle considered part of aerobic metabolism, even though O2 does not appear in any of its catalytic reaction?arrow_forward
- Aside from the reduction of FAD to FADH2, what is the importance of the oxidation of succinate to fumarate in the citric acid cycle?arrow_forwardWhich one of the five steps of the pyruvate dehydrogenase complex reaction is most likely to be metabolically irreversible? Explain.arrow_forwardWhat step in the citric acid cycle is inhibited by fluoroacetate treatment?arrow_forward
- BiochemistryBiochemistryISBN:9781305577206Author:Reginald H. Garrett, Charles M. GrishamPublisher:Cengage LearningConcepts of BiologyBiologyISBN:9781938168116Author:Samantha Fowler, Rebecca Roush, James WisePublisher:OpenStax College