a)
Interpretation:
Using an alkylation reaction as the key step how the compound shown can be prepared is to be given.
Concept introduction:
An alkylation reaction is used to introduce a methyl or a primary alkyl group in α- position of aTo give:
Using an alkylation reaction as the key step how to prepare the compound shown.
b)
Interpretation:
Using an alkylation reaction as the key step how the compound shown can be prepared.
Concept introduction:
An alkylation reaction is used to introduce a methyl or a primary alkyl group in α- position of a ketone, ester or nitrile by a SN2 reaction of the enolate ion with an alkyl halide. Thus by looking at α- carbon of the product the alkyl halide to be used in the reaction can be identified. The enolate ion can be produced by using lithium diisopropylamide (LDA).
To give:
Using an alkylation reaction as the key step how to prepare the compound shown.
c)
Interpretation:
Using an alkylation reaction as the key step how the compound shown can be prepared.
Concept introduction:
An alkylation reaction is used to introduce a methyl or a primary alkyl group in α- position of a ketone, ester or nitrile by aSN2reaction of the enolate ion with an alkyl halide. Thus by looking at α- carbon of the product the alkyl halide to be used in the reaction can be identified. The enolate ion can be produced by using lithium diisopropylamide (LDA).
To give:
Using an alkylation reaction as the key step how to prepare the compound shown.
d)
Interpretation:
Using an alkylation reaction as the key step how the compound shown can be prepared.
Concept introduction:
An alkylation reaction is used to introduce a methyl or a primary alkyl group in α- position of a ketone, ester or nitrile by a SN2 reaction of the enolate ion with an alkyl halide. Thus by looking at α- carbon of the product the alkyl halide to be used in the reaction can be identified. The enolate ion can be produced by using lithium diisopropylamide (LDA).
To give:
Using an alkylation reaction as the key step how to prepare the compound shown.
e)
Interpretation:
Using an alkylation reaction as the key step how the compound shown can be prepared.
Concept introduction:
An alkylation reaction is used to introduce a methyl or a primary alkyl group in α- position of a ketone, ester or nitrile by a SN2 reaction of the enolate ion with an alkyl halide. Thus by looking at α- carbon of the product the alkyl halide to be used in the reaction can be identified. The enolate ion can be produced by using lithium diisopropylamide (LDA).
To give:
Using an alkylation reaction as the key step how to prepare the compound shown.
f)
Interpretation:
Using an alkylation reaction as the key step how the compound shown can be prepared.
Concept introduction:
An alkylation reaction is used to introduce a methyl or a primary alkyl group in α- position of a ketone, ester or nitrile by a SN2 reaction of the enolate ion with an alkyl halide. Thus by looking at α- carbon of the product the alkyl halide to be used in the reaction can be identified. The enolate ion can be produced by using lithium diisopropylamide (LDA).
To give:
Using an alkylation reaction as the key step how to prepare the compound shown.
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