The compound A in the given synthesis of the analogs of anthracycline antibiotics is to be identified. Concept introduction: The reaction that involves the rearrangement of the esters of phenol into a hydroxyl aryl ketone with the use of Lewis acid catalyst is called as Fries rearrangement reaction. The relocation of the phenol ester acyl group to the aryl ring takes place in this type of reaction.

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Definition Definition Organic compounds that have a carbonyl group, C = O, as their functional group. The carbonyl group in ketones is placed somewhere in the middle of the molecular structure, which means, the C=O is attached to two alkyl groups or benzene rings. Just like all other homologous series, the naming of ketones is done using a common suffix “-one”. The general molecular formula is C n H 2n O. Functional group of a ketone

Chapter 23, Problem 18P

Interpretation Introduction

Interpretation: The compound A in the given synthesis of the analogs of anthracycline antibiotics is to be identified.

Concept introduction:

The reaction that involves the rearrangement of the esters of phenol into a hydroxyl aryl ketone with the use of Lewis acid catalyst is called as Fries rearrangement reaction.

The relocation of the phenol ester acyl group to the aryl ring takes place in this type of reaction.

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16. When cis-1,2-cyclopentanediol reacts with acetone in dry HCl, compound M is formed. What do you expect the hydrolysis of compound M to be when subjected (i) to base; and, (ii) acid A. resistant to base; resistant to acid B. resistant to base; readily hydrolyzed by acid C. readily hydrolyzed by base; resistant to acid D. readily hydrolyzed by base; readily hydorlyzed by acid

16. When cis-1,2-cyclopentanediol reacts with acetone in dry HCl, compound M is formed. What do you expect the hydrolysis of compound M to be when subjected (i) to base; and, (ii) acid a. resistant to base; resistant to acid b. resistant to base; readily hydrolyzed by acid c. readily hydrolyzed by base; resistant to acid d. readily hydrolyzed by base; readily hydorlyzed by acid 17. Following (16), would you expect that a similar compound be formed if the reactant was trans-1,2-cyclopentanediol? Why is this so? a. Yes; hydroxyl groups are on opposite side b. No; hydroxyl groups are on opposite site c. Yes; hydroxyl groups are on the same side d. No; hydroxyl groups are on the same side

Shown below is the 1H NMR spectrum of the alkyl bromide used to make the phosphonium ylide that reacts with a ketone in a Wittig reaction to form acompound with molecular formula C11H14. What product is obtained from the Wittig reaction?

Answer 2

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Definition Definition Organic compounds that have a carbonyl group, C = O, as their functional group. The carbonyl group in ketones is placed somewhere in the middle of the molecular structure, which means, the C=O is attached to two alkyl groups or benzene rings. Just like all other homologous series, the naming of ketones is done using a common suffix “-one”. The general molecular formula is C n H 2n O. Functional group of a ketone

Chapter 23, Problem 18P

Interpretation Introduction

Interpretation: The compound A in the given synthesis of the analogs of anthracycline antibiotics is to be identified.

Concept introduction:

The reaction that involves the rearrangement of the esters of phenol into a hydroxyl aryl ketone with the use of Lewis acid catalyst is called as Fries rearrangement reaction.

The relocation of the phenol ester acyl group to the aryl ring takes place in this type of reaction.

Expert Solution & Answer

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Check out a sample textbook solution

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Answer 3

Question

Definition Definition Organic compounds that have a carbonyl group, C = O, as their functional group. The carbonyl group in ketones is placed somewhere in the middle of the molecular structure, which means, the C=O is attached to two alkyl groups or benzene rings. Just like all other homologous series, the naming of ketones is done using a common suffix “-one”. The general molecular formula is C n H 2n O. Functional group of a ketone

Chapter 23, Problem 18P

Interpretation Introduction

Interpretation: The compound A in the given synthesis of the analogs of anthracycline antibiotics is to be identified.

Concept introduction:

The reaction that involves the rearrangement of the esters of phenol into a hydroxyl aryl ketone with the use of Lewis acid catalyst is called as Fries rearrangement reaction.

The relocation of the phenol ester acyl group to the aryl ring takes place in this type of reaction.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Organic compounds that have a carbonyl group, C = O, as their functional group. The carbonyl group in ketones is placed somewhere in the middle of the molecular structure, which means, the C=O is attached to two alkyl groups or benzene rings. Just like all other homologous series, the naming of ketones is done using a common suffix “-one”. The general molecular formula is C n H 2n O. Functional group of a ketone

Chapter 23, Problem 18P

Interpretation Introduction