Concept explainers
To determine: The reaction of the IMP
Concept introduction: Synthesis of purine yields inosine monophosphate (IMP). IMP is a precursor of adenosine monophosphate (AMP). The urea cycle is important to remove the amino group from the body.
Explanation of Solution
Explanation:
The reaction in which aspartate is added to the IMP and adenylosuccinate lyase take away fumarate by leaving the amino group. Urea is synthesized in the liver by urea cycle. The urea is secreted into the blood stream and after the filtration in kidney it excretes in the urine. In the urea cycle, after addition of aspartate to the citrulline, argininosuccinase take away fumarate by leaving an amino group. Therefore, the reaction catalyzed by adenylosuccinate lyase in IMP
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Chapter 23 Solutions
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