Genetics: A Conceptual Approach
6th Edition
ISBN: 9781319050962
Author: Benjamin A. Pierce
Publisher: W. H. Freeman
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Question
Chapter 23.1, Problem 3COQ
Summary Introduction
To outline:
Knudson’s two-hit hypothesis of retinoblastoma and also describe the way in which it helps to explain unilateral and bilateral cases of retinoblastoma.
Introduction:
Alfred Knudson in 1971, proposed a model to explain the genetic basis for cancer. He was studying retinoblastoma (develops in one eye but sometimes appears in both) and proposed that retinoblastoma results from separate genetic defects mainly two and both of which are required for the development of cancer.
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Genetics: A Conceptual Approach
Ch. 23.1 - Prob. 1CCCh. 23.1 - Prob. 1COQCh. 23.1 - Prob. 2COQCh. 23.1 - Prob. 3COQCh. 23.1 - Prob. 4COQCh. 23.1 - Prob. 22AQPCh. 23.1 - Prob. 23AQPCh. 23.1 - Prob. 2TPSQCh. 23.1 - Prob. 3TPSQCh. 23.1 - Prob. 4TPSQ
Ch. 23.2 - Prob. 2CCCh. 23.2 - Prob. 3CCCh. 23.2 - Prob. 4CCCh. 23.2 - Prob. 5CCCh. 23.2 - Prob. 5COQCh. 23.2 - Prob. 6COQCh. 23.2 - Prob. 7COQCh. 23.2 - Prob. 8COQCh. 23.2 - Prob. 9COQCh. 23.2 - Prob. 10COQCh. 23.2 - Prob. 11COQCh. 23.2 - Prob. 12COQCh. 23.2 - Prob. 13COQCh. 23.2 - Prob. 24AQPCh. 23.2 - Prob. 25AQPCh. 23.2 - Prob. 26AQPCh. 23.2 - Prob. 27AQPCh. 23.2 - Prob. 28AQPCh. 23.2 - Prob. 33CQCh. 23.2 - Prob. 34CQCh. 23.2 - Prob. 35CQCh. 23.2 - Prob. 5TPSQCh. 23.3 - Prob. 6CCCh. 23.3 - Prob. 14COQCh. 23.3 - Prob. 15COQCh. 23.3 - Prob. 29AQPCh. 23.3 - Prob. 30AQPCh. 23.4 - Prob. 16COQCh. 23.5 - Prob. 7CCCh. 23.5 - Prob. 17COQCh. 23.5 - Prob. 18COQCh. 23.5 - Prob. 19COQCh. 23.5 - Prob. 31AQPCh. 23.6 - Prob. 20COQCh. 23.6 - Prob. 32AQPCh. 23.6 - Prob. 6TPSQCh. 23 - Prob. 21AQPCh. 23 - Prob. 1TPSQ
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