Concept explainers
To discuss:
The renin-angiotensin-aldosterone mechanism of regulating GFR; multiple effects of angiotensin II on the kidney and on the rest of the body.
Introduction:
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ANATOMY & PHYSIOLOGY THE UNITY OF FORM A
- True or false activation of the angiotensin in Cascade increases blood volume by increasing the reabsorption of NA+ CL- in the kidneysarrow_forwardtrue or false Aldosterone is required to restore water from loop of Henle, and reabsorption of Na+ from this segment is increased by ADH, allowing equilibration of water with the hyperosmotic interstitiumarrow_forwardKIDNEY FUNCTION IN REGULATION OF RENAL BLOOD FLOW, FLUIDS VOLUME AND REGULATION OF ENDOCRINEarrow_forward
- Sodium ion reabsorption from the filtrate into peritubular blood across the cells of this component of the nephron (marked by the black asterisk) Choose from the following: (A) is regulated by the binding of the hormone aldosterone (B) is not regulated by any hormone, but is determined by sodium ion concentration and filtrate flowarrow_forwardTubular secretiona. Secretion transports substances from plasma in the peritubular capillaries to the renal tubular fluid.b. Various organic compounds are secreted actively.c. Potassium and hydrogen ions are both secreted actively. Potassium ions are also secreted passivelyarrow_forwardDefine renin-angiotensin-aldosterone mechanismarrow_forward
- filtration pressure and determine whether it favors filtration or reabsorption. State whether this would correspond to the Given the general formula to determine capillary filtration is NFP = (BHP + IFOP) - (BCOP + IFHP), calculate the net Unknown Capillary End IFHP = 4 IFOP = 2 BHP = 14 BCOP = 28arrow_forwardRenin is an important proteolytic enzyme produced by the kidney, involved in the control of salt/water balance in the body. Explain the source of renin, how it is secreted and how it acts to ultimately influence plasma volume. A separate hormonal system exists for directly controlling kidney water reabsorption. Explain how this hormone is released and how it exerts its renal effects.arrow_forwardRenal is a process that yields relatively constant GFR with fluctuating blood pressure in the kidney, occurring through (two words) where the smooth muscle of the afferent arteriole constricts when stretched and a tubuloglomerular feedback mechanism which occurs when the are activated by rising NaCl concentrations and increased flow rates.arrow_forward
- Important for hormonal regulation of salt and water balance - Distal convoluted tubule - Proximal tubule - Collecting duct - Loop of henlearrow_forwardAtrial natriuretic peptide lowers blood pressure by increasing sodium reabsorption decreasing sodium reabsorption increasing sodium secretionarrow_forwardDescribe how each of the following functions in the extrinsic control of GFR: renin-angiotensin mechanism, natriuretic peptides, and sympathetic adrenergic activityarrow_forward
- Human Physiology: From Cells to Systems (MindTap ...BiologyISBN:9781285866932Author:Lauralee SherwoodPublisher:Cengage Learning