Concept explainers
To discuss:
The general term for substances acted upon by enzymes; the relevance of active sites to enzyme action; why the active sites limit the range of substances on which enzyme can act; and the name for its principle of selective action.
Introduction:
Enzymes are the most important substances that play a major role in the body’s
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Chapter 2 Solutions
LSC (CONCORDIA UNIV ST PAUL) BIO 315/316: B&N DPF Connect with APR and Phils Online Access for Anatomy and Physiology: The Unity of Form and Function 180 Day Access ENTRP
- Which of the following statements regarding enzyme catalysis is false? All options are false. Once formed, the transition state slowly proceeds to forming the product at a rate determined by cofactor binding The free energy of binding of the enzyme to the transition state is more favorable than the free energy of binding of the enzyme to the substrate The substrate and active site of the enzyme are solvated to promote enzyme-substrate interaction Once formed, the product dissociates from the enzyme after ATP hydrolysis in order to regenerate the active sitearrow_forwardGiven the four statements, which is the correct statement about the control of enzyme activity by phosphorylationarrow_forwardWhich of the following statements is true about effect of substrate concentration on enzyme activity ? The rate of reaction increases as the substrate concentration increases up to certain limit at which the reaction rate is maximal (Vmax.) At Vmax, the enzyme is completely saturated with the substrate, At Vmax, any increase in substrate concentration don't affect the reaction rate. All of themarrow_forward
- In _____________ inhibition, the EI complex readily dissociates and the enzyme is again available for substrate binding.arrow_forwardRegarding the physical condition (characteristics of the solution/environment) in which an enzyme finds itself: sometimes enzymes are most active at a certain level and still active but to a lesser degree at a level above or below the optimal level. Describe the likely reason for the enzyme’s decrement in function at levels other than the optimal level?arrow_forwardEnzymes are specific, they match with a specific and particular reactant during the reactions, the enzyme changes shape and cannot be used again true or falsearrow_forward
- Major product with mechanism.arrow_forwardThe site on the enzyme surface where the reactant fits is referred to as the __________arrow_forwardEnzymes are proteins that increase the rate of chemical reactions by lowering the energy activation required to facilitate the process. Explain the generalized and sequential enzyme mechanism of action (hint: from substrates to products).arrow_forward
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