Concept explainers
To determine: The base that is most likely to pair with hypoxanthine.
Concept introduction: Base pairing can be defined as the capability of
But there are some naturally modified purines and pyrimidine bases that exist in constituent of
Answer to Problem 1E
Correct answer: The base that is most likely to pair with hypoxanthine is cytosine.
Explanation of Solution
Explanation: Hypoxanthine is a naturally occurring modified form of purine base. Hypoxanthine is formed due to the mutational changes in the base adenine. Deamination of adenine bases leads to form hypoxanthine that pairs with the cytosine (instead of pairing with thymine base) because its structure resembles to guanine. Some usual structures such as tRNA molecule consists of hypoxanthine attached with ribose sugar in the form of inosine.
Conclusion: Hypoxanthine structure resembles to guanine base. Therefore, it is more likely to pair with cytosine that usually pair with guanine.
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Chapter 24 Solutions
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