Concept explainers
To determine: The number of histone variants in the human cell.
Concept introduction: Histones are the proteins that wind and pack DNA to form a compact structure called nucleosomes. There are five different types of histone proteins, namelyH1, H2A, H2B, H3, and H4. Apart from the major canonical histone types, there are many variants that provide the different functions to them.
To explain: How the histone variants differ from each other.
Concept introduction: Histones are the proteins that wind and pack DNA to form a compact structure called nucleosomes. There are five different types of histone proteins, namelyH1, H2A, H2B, H3, and H4. Apart from the major canonical histone types, there are many variants that provide the different functions to them.
To determine: The way how the histone variant CENP-A relates to the chromosomal structure.
Concept introduction: Histones are the proteins that wind and pack DNA to form a compact structure called nucleosomes. There are five different types of histone proteins, namelyH1, H2A, H2B, H3, and H4. Apart from the major canonical histone types, there are many variants that provide the different functions to them.
To determine: The histone variant that is associated with X-chromosome inactivation.
Concept introduction: Histones are the proteins that wind and pack DNA to form a compact structure called nucleosomes. There are five different types of histone proteins, namelyH1, H2A, H2B, H3, and H4. Apart from the major canonical histone types, there are many variants that provide the different functions to them.
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