Fundamentals of Biochemistry: Life at the Molecular Level
Fundamentals of Biochemistry: Life at the Molecular Level
5th Edition
ISBN: 9781118918401
Author: Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher: WILEY
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Chapter 24, Problem 1MTE
Summary Introduction

To determine: The number of histone variants in the human cell.

Concept introduction: Histones are the proteins that wind and pack DNA to form a compact structure called nucleosomes. There are five different types of histone proteins, namelyH1, H2A, H2B, H3, and H4. Apart from the major canonical histone types, there are many variants that provide the different functions to them.

Summary Introduction

To explain: How the histone variants differ from each other.

Concept introduction: Histones are the proteins that wind and pack DNA to form a compact structure called nucleosomes. There are five different types of histone proteins, namelyH1, H2A, H2B, H3, and H4. Apart from the major canonical histone types, there are many variants that provide the different functions to them.

Summary Introduction

To determine: The way how the histone variant CENP-A relates to the chromosomal structure.

Concept introduction: Histones are the proteins that wind and pack DNA to form a compact structure called nucleosomes. There are five different types of histone proteins, namelyH1, H2A, H2B, H3, and H4. Apart from the major canonical histone types, there are many variants that provide the different functions to them.

Summary Introduction

To determine: The histone variant that is associated with X-chromosome inactivation.

Concept introduction: Histones are the proteins that wind and pack DNA to form a compact structure called nucleosomes. There are five different types of histone proteins, namelyH1, H2A, H2B, H3, and H4. Apart from the major canonical histone types, there are many variants that provide the different functions to them.

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