CAMPBELL BIOLOGY IN FOCUS (LL)-W/MOD.MA
CAMPBELL BIOLOGY IN FOCUS (LL)-W/MOD.MA
3rd Edition
ISBN: 9780135686065
Author: Urry
Publisher: PEARSON
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Chapter 24, Problem 9TYU

FOCUS ON EVOLUTION

In patients infected with nonresistant strains of the tuberculosis bacterium, antibiotics can relieve symptoms in a few weeks. However, it takes much longer to halt the infection, and patients may discontinue treatment while bacteria are still present. How might this result in the evolution of drug-resistant pathogens?

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Some advocate stockpiling the drug Tamiflu in the event of an influenza pandemic. Others point out that wealthy, Western nations would have an unfair advantage because developing nations (where the pandemic is most likely to start) would not have access to this expensive antiviral. Furthermore, some fear that indiscriminate use of the drug would promote the evolution of resistant flu strains. Given these caveats, do you think developed nations should stockpile Tamiflu for the protection and treatment of their citizens? Explain your answer
There are concerns about overuse and misuse of antibacterial drugs, and the association of these with increased antibiotic resisstance in bacteria.  Of the following, which best explains this?      Antibiotic exposure directly causes many of bacterial in a population to mutate and develop new antibiotic resistance traits.     If antibiotic use occurs repeatedly in a person, the dosage of the drug needs to be increased to work in a patient’s system because he/she will develop physiological tolerance to the antibiotic.     Exposure to an antibiotic causes bacteria to die or become stronger; stronger bacteria will be better able to cope with additional exposures to any antibiotic drug, eventually becoming immune to all antibiotics.     Antibiotics kill susceptible cells and even a small number of existing resistant bacteria that survive will become the majority of the population that remains, leading to populations that are resistant to this drug.
Select all the statements that are true regarding the drug treatments available for infectious diseases.□ Antiviral drugs are harder to develop than antibiotics because viruses must use our cellular machinery replicate. □ Very few anti-parasitic drugs exist because diseases caused by Eukaryotes are extremely rare all over the world.□ Fewer drugs are available to treat Eukaryotic pathogens because their physiology and functions are very similar to our own.□ Development of antiparasitic drugs are a low priority because the diseases they treat tend to occur in poor countries, and drug companies can't make money.□ Antivirals may quit working because rates of viral mutation are very high.□ There are more antiviral drugs than atibiotics because antiviral drugs are very easy and cheap to make.
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