Lehninger Principles of Biochemistry (Instructor's)
Lehninger Principles of Biochemistry (Instructor's)
7th Edition
ISBN: 9781319117689
Author: nelson
Publisher: MAC HIGHER
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Chapter 25, Problem 13P
Summary Introduction

To determine: The advantage of the repair system in the cell that replaces GT base pair mismatch with GC base pairs.

Introduction:

Methyl directed mismatch repair mechanism inside the cell utilizes the function of MutH and MutS protein inside the cell. MutS forms a complex with MutL at the site of methylation causing mutation in DNA. MutH cleaves the unmethylated residues which are replaced by fresh nucleotides in the genome for mismatch repair.

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