Difference between the de novo synthesis and salvage-pathway synthesis of nucleotides should be determined Concept introduction: Purines and pyrimidines are the nucleotides, which are produced in the liver. They contain a molecule of sugar and phosphate. The location of nitrogen in both the nucleotides is different. Their pathways of synthesis are different, but they need a common phosphorylated 5-carbon monosaccharide.

Question

Want to see more full solutions like this?

Answer 1

Question

Chapter 25, Problem 1P

Interpretation Introduction

Interpretation:

Difference between the de novo synthesis and salvage-pathway synthesis of nucleotides should be determined

Concept introduction:

Purines and pyrimidines are the nucleotides, which are produced in the liver. They contain a molecule of sugar and phosphate. The location of nitrogen in both the nucleotides is different. Their pathways of synthesis are different, but they need a common phosphorylated 5-carbon monosaccharide.

Expert Solution & Answer

Answer to Problem 1P

De novo pathway includes the simpler substrates that are used to synthesize pyrimidines.

Salvage pathways include the preformed and recovered bases for the synthesis of purines.

Explanation of Solution

The difference between the de novo pathway and the salvage pathway is given as below:

De novo pathways	Salvage pathways
1. Simple substrates are used in the de novo pathways for the synthesis of nucleotides.	1. In the salvage pathways, bases are recovered, preformed, and reconnected to the ribose sugar.
2. It is used to synthesize all the pyrimidines. Only two precursors, aspartate, and carbamoyl phosphate, are required here.	2. It is used to synthesize the purines. Many substrates are required here for the synthesis of purines.

Conclusion

De novo pathway includes the simpler substrates that are used to synthesize pyrimidines.

Salvage pathways include the preformed and recovered bases for the synthesis of purines.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Students have asked these similar questions

Please help and explain the following question...thank you! Describe instances when a DNA mutation would not alter the function of a protein. Describe instances when a DNA mutation would alter the function of a protein

Modified TRUE or FALSE. Write the word TRUE if the statement is correct. If the statement is false, write the incorrect underlined word/s and indicate the correct word/s to make the statement true. Extreme temperatures and pH can cause permanent disruption of the protein primary structure(s) of enzymes that leads to loss of active site shape, loss of binding efficiency and activity.

ubiquitin attaches to proteins via many biochemical reactions, please explain how this attachment targets protein for degradation and describe the biochemical reactions.

Answer 2

Question

Chapter 25, Problem 1P

Interpretation Introduction

Interpretation:

Difference between the de novo synthesis and salvage-pathway synthesis of nucleotides should be determined

Concept introduction:

Purines and pyrimidines are the nucleotides, which are produced in the liver. They contain a molecule of sugar and phosphate. The location of nitrogen in both the nucleotides is different. Their pathways of synthesis are different, but they need a common phosphorylated 5-carbon monosaccharide.

Expert Solution & Answer

Answer to Problem 1P

De novo pathway includes the simpler substrates that are used to synthesize pyrimidines.

Salvage pathways include the preformed and recovered bases for the synthesis of purines.

Explanation of Solution

The difference between the de novo pathway and the salvage pathway is given as below:

De novo pathways	Salvage pathways
1. Simple substrates are used in the de novo pathways for the synthesis of nucleotides.	1. In the salvage pathways, bases are recovered, preformed, and reconnected to the ribose sugar.
2. It is used to synthesize all the pyrimidines. Only two precursors, aspartate, and carbamoyl phosphate, are required here.	2. It is used to synthesize the purines. Many substrates are required here for the synthesis of purines.

Conclusion

De novo pathway includes the simpler substrates that are used to synthesize pyrimidines.

Salvage pathways include the preformed and recovered bases for the synthesis of purines.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 3

Question

Chapter 25, Problem 1P

Interpretation Introduction

Interpretation:

Difference between the de novo synthesis and salvage-pathway synthesis of nucleotides should be determined

Concept introduction:

Purines and pyrimidines are the nucleotides, which are produced in the liver. They contain a molecule of sugar and phosphate. The location of nitrogen in both the nucleotides is different. Their pathways of synthesis are different, but they need a common phosphorylated 5-carbon monosaccharide.

Expert Solution & Answer

Answer to Problem 1P

De novo pathway includes the simpler substrates that are used to synthesize pyrimidines.

Salvage pathways include the preformed and recovered bases for the synthesis of purines.

Explanation of Solution

The difference between the de novo pathway and the salvage pathway is given as below:

De novo pathways	Salvage pathways
1. Simple substrates are used in the de novo pathways for the synthesis of nucleotides.	1. In the salvage pathways, bases are recovered, preformed, and reconnected to the ribose sugar.
2. It is used to synthesize all the pyrimidines. Only two precursors, aspartate, and carbamoyl phosphate, are required here.	2. It is used to synthesize the purines. Many substrates are required here for the synthesis of purines.

Conclusion

De novo pathway includes the simpler substrates that are used to synthesize pyrimidines.

Salvage pathways include the preformed and recovered bases for the synthesis of purines.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 4

Question

Chapter 25, Problem 1P

Interpretation Introduction

Interpretation:

Difference between the de novo synthesis and salvage-pathway synthesis of nucleotides should be determined

Concept introduction:

Purines and pyrimidines are the nucleotides, which are produced in the liver. They contain a molecule of sugar and phosphate. The location of nitrogen in both the nucleotides is different. Their pathways of synthesis are different, but they need a common phosphorylated 5-carbon monosaccharide.

Expert Solution & Answer

Answer to Problem 1P

De novo pathway includes the simpler substrates that are used to synthesize pyrimidines.

Salvage pathways include the preformed and recovered bases for the synthesis of purines.

Explanation of Solution

The difference between the de novo pathway and the salvage pathway is given as below:

De novo pathways	Salvage pathways
1. Simple substrates are used in the de novo pathways for the synthesis of nucleotides.	1. In the salvage pathways, bases are recovered, preformed, and reconnected to the ribose sugar.
2. It is used to synthesize all the pyrimidines. Only two precursors, aspartate, and carbamoyl phosphate, are required here.	2. It is used to synthesize the purines. Many substrates are required here for the synthesis of purines.

Conclusion

De novo pathway includes the simpler substrates that are used to synthesize pyrimidines.

Salvage pathways include the preformed and recovered bases for the synthesis of purines.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 5

Chapter 25, Problem 1P

Interpretation Introduction

Interpretation:

Difference between the de novo synthesis and salvage-pathway synthesis of nucleotides should be determined

Concept introduction:

Purines and pyrimidines are the nucleotides, which are produced in the liver. They contain a molecule of sugar and phosphate. The location of nitrogen in both the nucleotides is different. Their pathways of synthesis are different, but they need a common phosphorylated 5-carbon monosaccharide.

Expert Solution & Answer

Answer to Problem 1P

De novo pathway includes the simpler substrates that are used to synthesize pyrimidines.

Salvage pathways include the preformed and recovered bases for the synthesis of purines.

Explanation of Solution

The difference between the de novo pathway and the salvage pathway is given as below:

De novo pathways	Salvage pathways
1. Simple substrates are used in the de novo pathways for the synthesis of nucleotides.	1. In the salvage pathways, bases are recovered, preformed, and reconnected to the ribose sugar.
2. It is used to synthesize all the pyrimidines. Only two precursors, aspartate, and carbamoyl phosphate, are required here.	2. It is used to synthesize the purines. Many substrates are required here for the synthesis of purines.

Conclusion

De novo pathway includes the simpler substrates that are used to synthesize pyrimidines.

Salvage pathways include the preformed and recovered bases for the synthesis of purines.

Answer 6

Chapter 25, Problem 1P

Interpretation Introduction

Interpretation:

Difference between the de novo synthesis and salvage-pathway synthesis of nucleotides should be determined

Concept introduction:

Purines and pyrimidines are the nucleotides, which are produced in the liver. They contain a molecule of sugar and phosphate. The location of nitrogen in both the nucleotides is different. Their pathways of synthesis are different, but they need a common phosphorylated 5-carbon monosaccharide.

Expert Solution & Answer

Answer to Problem 1P

De novo pathway includes the simpler substrates that are used to synthesize pyrimidines.

Salvage pathways include the preformed and recovered bases for the synthesis of purines.

Explanation of Solution

The difference between the de novo pathway and the salvage pathway is given as below:

De novo pathways	Salvage pathways
1. Simple substrates are used in the de novo pathways for the synthesis of nucleotides.	1. In the salvage pathways, bases are recovered, preformed, and reconnected to the ribose sugar.
2. It is used to synthesize all the pyrimidines. Only two precursors, aspartate, and carbamoyl phosphate, are required here.	2. It is used to synthesize the purines. Many substrates are required here for the synthesis of purines.

Conclusion

De novo pathway includes the simpler substrates that are used to synthesize pyrimidines.

Salvage pathways include the preformed and recovered bases for the synthesis of purines.

Answer 7

Chapter 25, Problem 1P

Interpretation Introduction

Interpretation:

Difference between the de novo synthesis and salvage-pathway synthesis of nucleotides should be determined

Concept introduction:

Purines and pyrimidines are the nucleotides, which are produced in the liver. They contain a molecule of sugar and phosphate. The location of nitrogen in both the nucleotides is different. Their pathways of synthesis are different, but they need a common phosphorylated 5-carbon monosaccharide.

Answer 8

Expert Solution & Answer

Answer to Problem 1P

De novo pathway includes the simpler substrates that are used to synthesize pyrimidines.

Salvage pathways include the preformed and recovered bases for the synthesis of purines.

Answer 9

Expert Solution & Answer

Answer 10

Expert Solution & Answer

Answer 11

Explanation of Solution

The difference between the de novo pathway and the salvage pathway is given as below:

De novo pathways	Salvage pathways
1. Simple substrates are used in the de novo pathways for the synthesis of nucleotides.	1. In the salvage pathways, bases are recovered, preformed, and reconnected to the ribose sugar.
2. It is used to synthesize all the pyrimidines. Only two precursors, aspartate, and carbamoyl phosphate, are required here.	2. It is used to synthesize the purines. Many substrates are required here for the synthesis of purines.