Fund. of General, Org... -Masteringchem.
Fund. of General, Org... -Masteringchem.
8th Edition
ISBN: 9780134143330
Author: McMurry
Publisher: PEARSON
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Chapter 25, Problem 25.24AP

(a)

Interpretation Introduction

Interpretation:

Structure of α-ketoacid formed from the transamination of Isoleucine has to be drawn.

Concept introduction:

  • Transamination of amino acid is the reaction in which amino group is converted to keto acid and formation of a new amino acid takes place.
  • The reaction is the interchange of amino group from given amino acid with the keto group from α-ketoglutarate. During transamination reaction α-ketoglutarate gives glutamate as the product. The product from the amino acid is the keto group.
  • Oxidative deamination is the removal of NH4+ bonded to αcarbon and replacing them by a C=O gives the desired α-ketoacid.

(b)

Interpretation Introduction

Interpretation:

Structure of α-ketoacid formed from the transamination of Valine has to be drawn.

Concept introduction:

  • Transamination of amino acid is the reaction in which amino group is converted to keto acid and formation of a new amino acid takes place.
  • The reaction is the interchange of amino group from given amino acid with the keto group from α-ketoglutarate. During transamination reaction α-ketoglutarate gives glutamate as the product. The product from the amino acid is the keto group.
  • Oxidative deamination is the removal of NH4+ bonded to αcarbon and replacing them by a C=O gives the desired α-ketoacid.

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Students have asked these similar questions
Name the α-ketoacid that is formed by the transamination of each of the following amino acids: (a) Alanine (d) Leucine (b) Aspartate (e) Phenylalanine (c) Glutamate (f) Tyrosine
Name and draw the structure of the a-keto acid resulting when each of the following amino acids undergoes transamination with a-ketoglutarate: (a) aspartate, (b) glutamate, (c) alanine, (d) phenylalanine.
Based on your knowledge of the natural amino acids, what would you expect pKa of the sidechain of beta-(aminomethyl)succinic acid to be? Draw an appropriate titration curve for beta-(aminomethyl)succinic acid, labeling the axes, indicating the equivalence points and the pKavalues, and use a drawing to show the protonated/deprotonated forms.

Chapter 25 Solutions

Fund. of General, Org... -Masteringchem.

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