Lehninger Principles of Biochemistry
Lehninger Principles of Biochemistry
7th Edition
ISBN: 9781464126116
Author: David L. Nelson, Michael M. Cox
Publisher: W. H. Freeman
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Chapter 26, Problem 12P

(a)

Summary Introduction

To suggest: A technique that will allow the detection of rifampicin-resistant strain containing the particular mutant protein encoded by mutation in specific 69 bp region of rpoB.

Introduction:

Proteins are the large chains of amino acids. These amino acids form a complex structure that is required in each and every reaction. Rifampicin is an antibiotic, which is used to treat bacterial infection such as tuberculosis. It is produced from Streptomyces mediterranei. Rifampicin has a broad antibacterial spectrum.

(b)

Summary Introduction

To suggest: A technique that will identify the mutant form of rpoB .

Introduction:

Rifampicin is an antibiotic which is used to treat bacterial infection such as tuberculosis. It is produced from Streptomyces mediterranei. Rifampicin has a broad antibacterial spectrum.

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