Pearson eText for Biochemistry: Concepts and Connections -- Instant Access (Pearson+)
2nd Edition
ISBN: 9780137533114
Author: Dean Appling, Spencer Anthony-Cahill
Publisher: PEARSON+
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Chapter 26, Problem 2P
Is attenuation likely to be involved in eukaryotic gene regulation? Briefly explain your answer.
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Provide a detailed description of gene expression and control in prokaryotes. Provide a detailed description of proteins critical for this process. (please hand draw a figure showing gene expression and control in prokaryotes and the proteins involved)
What is meant by the term attenuation? Is it an example of generegulation during transcription or translation? Explain your answer.
Compare the control of gene regulation in eukaryotes and prokaryotes at the level of initiation of transcription. How do the regulatory mechanisms work? What are the similarities and differences in these two types of organisms in terms of the specific components of the regulatory mechanisms? Address how the differences or similarities relate to the biological context of the control of gene expression.
Chapter 26 Solutions
Pearson eText for Biochemistry: Concepts and Connections -- Instant Access (Pearson+)
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- Briefly describe an experiment you could perform to isolate ER-associated ribosomes and test if these are capable of translating mRNAs that code for cytoplasmic proteins.arrow_forwardHelp me pleasearrow_forwardGenes can be transcribed into mRNA, in the case of protein coding genes, or into RNA, in the case of genes such as those that encode ribosomal or transfer RNAs. Define a gene. For the following characteristics, state whether they apply to (a) continuous, (b) simple, or (c) complex transcription units.i. Found in eukaryotesii. Contain intronsiii. Capable of making only a single protein from a given genearrow_forward
- i)Describe attenuation control and how it is used to regulate gene expression. ii)Give a specific example of how this works? iii)Could this be used in eukaryotes? why ?or why not?arrow_forwardYou are teaching a class on the regulation of eukaryotic gene expression. In order to demonstrate this complex process, you decide to draw for the class a typical eukaryotic gene/transcription unit with its major regions, such as the promoter regions, where the RNA polymerase II and transcription factors would bind From the list given - choose all components that you think are part of a typical eukaryotic gene From the list given - choose all the regulatory sequences that you think would control the expression of this eukaryotic gene From the list given - choose all of the regulatory proteins that would bind the eukaryotic gene to control its expressionarrow_forwardOn the basis of these results, is the C sequence an operator or a regulator gene? Explain your reasoning.arrow_forward
- For each of the following, identify whether that sequence or feature of a typical protein-coding gene would be recognizable in the specified molecule in a typical prokaryotic cell. 5' UTR in DNA? 5' UTR in mRNA? Shine-Dalgarno in DNA? Shine-Dalgarno in polypeptide? Promoter in RNA? Promoter in polypeptide sequence? Stop codon in mRNA? Stop codon in the polypeptide sequence? [Choose ] [Choose ] [Choose ] [Choose ] [Choose ] [Choose ] [Choose ] [Choose ] > <arrow_forwardUsing three examples, describe how allosteric sites are important in the function of genetic regulatory proteins.arrow_forwardEukaryotes have a multitude of ways of regulating gene expression. Why are all these regulatory mechanisms necessary to the functioning of a eukaryotic organism?arrow_forward
- What is meant by the term attenuation? Is it an example of gene regulation at the level of transcription or translation? Explain your answerarrow_forwardSelect the following descriptions of gene transcription regulation in eukaryotes that are post-translational: Select 2 correct answer(s) O A) Length of poly A tail B) Chromatin modification C) Destruction of protein before/after modifications by a proteosome U D) Alternative splicing of mRNA molecule E) Acetylation of histone tails F) Binding of activators to enhancers regions on the DNA G) destruction of mRNA by RNA interference O H) DNA methylation UI) Addition of functional groups to a fully formed proteinarrow_forwardGene X codes for a protein in eukaryotes. A mutated eukaryotic cell contains an altered base-pair in an intron of gene X. Which would be the most likely effect of this mutation on the biomolecules in the cell? The amount of pre-mRNA transcribed from gene X would be less than normal. The amount of functional protein corresponding to gene X would be less than normal. The ability of snRNAs to form a spliceosome would be diminished. The breakdown of mature mRNA corresponding to gene X would be fasterarrow_forward
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