Chapter 26.4, Problem 6P

Interpretation Introduction

Interpretation:

A retrosynthetic analysis to plan a synthesis of valine from $\text{3-methylbutanoic acid}$ is to be discussed and equations for the synthesis are to be written.

Concept Introduction:

Amino acids can be synthesized by the reaction of an $\text{α-halo carboxylic acid}$ with ammonia.

This is called as nucleophilic substitution reaction.

$\text{α-halo carboxylic acid}$ can be prepared by the reaction of halogens with the carboxylic acids.

Phosphorus tribromide is used to promote the halogenation in this reaction.