ORGANIC CHEMISTRY (LOOSELEAF)-PACKAGE
ORGANIC CHEMISTRY (LOOSELEAF)-PACKAGE
10th Edition
ISBN: 9781260008562
Author: Carey
Publisher: MCG
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Chapter 26.4, Problem 6P
Interpretation Introduction

Interpretation:

A retrosynthetic analysis to plan a synthesis of valine from 3-methylbutanoic acid is to be discussed and equations for the synthesis are to be written.

Concept Introduction:

Amino acids can be synthesized by the reaction of an α-halo carboxylic acid with ammonia.

This is called as nucleophilic substitution reaction.

α-halo carboxylic acid can be prepared by the reaction of halogens with the carboxylic acids.

Phosphorus tribromide is used to promote the halogenation in this reaction.

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