A retrosynthetic analysis to plan a synthesis of isoleucine from 2-methyl-1-butanol is to be used and equations for the synthesis are to be written. Concept Introduction: Amino acids can be synthesized by the reaction of an aldehyde with NH 4 Cl and NaCN . It is known as the Strecker synthesis. This is a double nucleophilic addition reaction that converts the aldehyde to an amino acid having one more carbon atom. Hydrolysis of the nitrile group converts the nitrile to the carboxylic acid group. Aldehydes can be obtained by the oxidation of primary alcohols with pyridinium chlorochromate. This reagent stops the oxidation at the aldehyde stage.

Question

Want to see the full answer?

Answer 1

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 26.4, Problem 7P

Interpretation Introduction

Interpretation:

A retrosynthetic analysis to plan a synthesis of isoleucine from 2-methyl-1-butanol is to be used and equations for the synthesis are to be written.

Concept Introduction:

Amino acids can be synthesized by the reaction of an aldehyde with NH4Cl and NaCN. It is known as the Strecker synthesis.

This is a double nucleophilic addition reaction that converts the aldehyde to an amino acid having one more carbon atom.

Hydrolysis of the nitrile group converts the nitrile to the carboxylic acid group.

Aldehydes can be obtained by the oxidation of primary alcohols with pyridinium chlorochromate. This reagent stops the oxidation at the aldehyde stage.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Write the reaction between Phthalic Anhydride and Resorcinol to produce Fluorescein

please don't provide handwrittin solution... Synthesis

For the identification tests of amines and amides. What would be the Composition/Reagent used for: - Hinsberg - Quinhydrone - Ramini - Alkaline Hydrolysis - Acid Hydrolysis - Nitrous acid test

Answer 2

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 26.4, Problem 7P

Interpretation Introduction

Interpretation:

A retrosynthetic analysis to plan a synthesis of isoleucine from 2-methyl-1-butanol is to be used and equations for the synthesis are to be written.

Concept Introduction:

Amino acids can be synthesized by the reaction of an aldehyde with NH4Cl and NaCN. It is known as the Strecker synthesis.

This is a double nucleophilic addition reaction that converts the aldehyde to an amino acid having one more carbon atom.

Hydrolysis of the nitrile group converts the nitrile to the carboxylic acid group.

Aldehydes can be obtained by the oxidation of primary alcohols with pyridinium chlorochromate. This reagent stops the oxidation at the aldehyde stage.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 26.4, Problem 7P

Interpretation Introduction

Interpretation:

A retrosynthetic analysis to plan a synthesis of isoleucine from 2-methyl-1-butanol is to be used and equations for the synthesis are to be written.

Concept Introduction:

Amino acids can be synthesized by the reaction of an aldehyde with NH4Cl and NaCN. It is known as the Strecker synthesis.

This is a double nucleophilic addition reaction that converts the aldehyde to an amino acid having one more carbon atom.

Hydrolysis of the nitrile group converts the nitrile to the carboxylic acid group.

Aldehydes can be obtained by the oxidation of primary alcohols with pyridinium chlorochromate. This reagent stops the oxidation at the aldehyde stage.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 26.4, Problem 7P

Interpretation Introduction