Chapter 27, Problem 14P

(a)

Summary Introduction

To explain: The features of tRNA^Ala which are recognized by Ala-tRNA synthetase.

Introduction:

RNA (ribonucleic acid) is a nucleic acid and acts as the genetic material in viruses. It performs various other functions such as coding, decoding, expression of genes, and regulation. One of the types of RNA is tRNA (transfer RNA).

(b)

Summary Introduction

To describe: Consequence of C→G mutation in third position of anticodon of tRNA^Ala.

Introduction:

There are twenty amino acids which are coded by 64 codons. So it is obvious that there are certain amino acids which are coded by more than one codon. This property is known as degeneracy of codons.

(c)

Summary Introduction

To describe: Other kinds of mutations that would result in insertion of proline in place of alanine.

Introduction:

Mutation is the alteration in the sequence of the nucleotide of genome of extrachromosomal DNA, virus or an organism. Mutations can be insertion, deletion or substitution of one or more nucleotide base. In substitution mutation, single nucleotide is exchanged for another nucleotide.

(d)

Summary Introduction

To describe: The reason behind the absence of this type of mutation in natural population.

Introduction:

Mutation is the alteration in the sequence of the nucleotide of genome of extrachromosomal DNA, virus or an organism. Mutations can be insertion, deletion or substitution of one or more nucleotide base. In substitution mutation, single nucleotide is exchanged for another nucleotide.