Concept explainers
(a)
Interpretation:
RQ value for glucose oxidation and tripalmitoylglycerol should be calculated.
Concept introduction:
RQ (respiratory quotient) value is the ratio of the volume of carbon dioxide produced to the amount of oxygen gas required in respiration process over a fixed period of time. Its value can be zero, less than one, one, and more than one.
(b)
Interpretation:
The use of RQ measurements of different energy sources during intense exercise should be determined.
Concept introduction:
RQ (respiratory quotient) value is the ratio of the volume of carbon dioxide produced to the amount of oxygen gas required in the respiration process over a fixed period of time. Its value can be zero, less than one, one, and more than one.
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Chapter 27 Solutions
BIOCHEMISTRY 2 TERM ACCESS
- Individuals with a thiamine-deficient diet have relatively high levels of pyruvate in their blood. Explain this in biochemical terms. .arrow_forwardA. What would be the effect of barbiturate abuse on oxidative phosphorylation ? B. What is the biochemical basis of carbon monoxide fatility?arrow_forwardCalculate the RQ resulting from the catabolism of (a) acetic acid and (b) glycerol trioleate. Be sure to subtract the water resulting from internal oxidation and assume that all of the oxygen in the molecule is used in this internal oxidation.arrow_forward
- Show sequentially, the total ATP Yield and the net ATP Yield in the complete oxidation of Glucose (from Glycolysis to Oxidative Phosphorylation) in the Muscle and Heart Tissues of a man. Indicate the differences in the ATP yield in both tissues.arrow_forwarda) describe the overall reaction catalyzed by the pyruvate dehydrogenase Situational Problems I. Oxidative decarboxylation of pyruvate and the TCA cycle in muscles are stimulated by increased aerobic excrcise. These processes operate only when O, is present, although oxygen does not participate directly in these processes. Explain why oxidative decarboxylation of pyruvate is activated under aerobic conditions. For the answer: a) describe the overall reaction catalyzed by the pyruvate complex (PDH) and its regulation; b) outline the intermediates and enzymes of the TCA cycle; c) explain the relationship between the reactions of PDH and the TCA cycle and the respiratory chain.arrow_forwardA. Briefly explain the signaling pathway by which the liver coverts the stored carbohydrate to glucose and transports it to blood at low blood glucose level. In your answer, the signal pathway, source of glucose, key enzymes and proteins should be described. B. The diagram shows some of the reactions of respiration. Glucose Triose phosphate Pyruvate Lactate Acetylcoenzyme A (i) In the diagram on the Answer Sheet, draw and label by arrow to show the reaction that (a) requires ATP, and (b) produces CO2. (ii) In what condition and why is pyruvate converted to lactate?arrow_forward
- Calculate the net ATP yield from monounsaturated oleic acid (18:1).Hint: Remember the step that bypasses acyl-CoA dehydrogenase.arrow_forwardPredict which one of the five steps of the a-ketoglutarate dehydrogenase complex reaction is metabolically irreversible under physiological conditions and explain why.arrow_forwardDiscuss how the isozymic forms of acetyl CoA carboxylase regulate fatty acid metabolism. Explain the reciprocal regulation of fatty acid production and breakdown, as well as the numerous mechanisms that are used to accomplish this control.arrow_forward
- Calculate the total ATP produced by the complete oxidation of a triglyceride composed of three palmitic acids in the liver. Be sure to indicate the specific steps involved and their corresponding ATP (or ATP equivalent).arrow_forwardLong explanations are not needed. Direct answers would suffice. a. Ribose-5-phosphate is produced by oxidative decarboxylation of 6-phosphogluconate catalyzed by the enzyme glucose-6-phosphate dehydrogenase. I. True II. False b. The pentose phosphate pathway occurs in the mitochondrion of tissues actively engaged in synthesis of fatty acids. I. True II. Falsearrow_forwardWorksheet on Computation of ATP yield from Fatty acid metabolism. Consider docosanoic acid, C21H43CO2H a. Label alpha (a) and beta ( B) carbons b. Draw the acyl COA derived from this fatty acid c. How many acetyl CoA molecules are formed by complete B-oxidation? d. How many cycles of B- oxidation are needed for complete oxidation? e. How many molecules of ATP are formed from the complex catabolism of this fatty acid.arrow_forward
- BiochemistryBiochemistryISBN:9781305577206Author:Reginald H. Garrett, Charles M. GrishamPublisher:Cengage Learning