EBK BIOCHEMISTRY
8th Edition
ISBN: 9781319116361
Author: BERG
Publisher: W.H. Freeman & Company
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Question
Chapter 28, Problem 9P
Interpretation Introduction
Interpretation:
The reason due to which the activation of telomerase gene causes cell to become cancerous needs to be explained.
Concept introduction:
Telomerase is the enzyme responsible for repair of the extend of telomeres. Telomerase regulates check on tumor cells. These are made up of proteins and RNA subunits.
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Polymerase inhibition. Cordycepin inhibits poly(A) synthesis at low
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NH2
H.
он
Cordycepin (3'-deoxyadenosine)
a. What is the basis of inhibition by cordycepin?
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True or False. Topoisomerase I does not require ATP to break and rejoin DNA strands because the energy of the phospho-diester bond is stored transiently in a phospho-tyrosine linkage in the enzyme’s active site. Explain your answer in 2-3 sentences.
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(yellow) but farther upstream.
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5' CCTATTGGTCTATTITCCACCCITAGGCTGCTG 3'
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