BIOCHEMISTRY W/1 TERM ACHEIVE ACCESS
9th Edition
ISBN: 9781319425746
Author: BERG
Publisher: MAC HIGHER
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Chapter 32, Problem 15P
Interpretation Introduction
Interpretation:
The examples for the control of gene expression should be given.
Concept introduction:
The gene expression is the phenomenon in which the genetic information encoded in genes is transformed into a functional protein.
Two important processes that control gene expression are transcription and translation. While the former deals with the synthesis of messenger RNA via the action of enzyme RNA polymerase the latter deals with mRNA directed synthesis of protein.
Certain specific regions, for instance, promoter, enhancers, and silencers, known as gene control regions, exist in the genomic DNA which is in transcription.
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Genetic expression in general can be regulated at various stages. Identify specific processes that control gene expression at the:
a. transcription level -
b. post-transcription level -
c. translation level -
Determine whether the following will increase or decrease gene expression:
mRNA degradation
mRNA capping
Binding of a transcriptional activator
Ubiquitination of a protein and targeting to the proteasome
Given the following schematic for a gene and its associated regulatory regions, answer the following questions by placing the correct letter in the provided blanks
please put in the correct letter for the questions
What region would provide cell type-specific expression of genes? region
What site would significantly increase gene expression rates? = region
What region or regions of this gene’s coding sequence are expressed as amino acids = region
Chapter 32 Solutions
BIOCHEMISTRY W/1 TERM ACHEIVE ACCESS
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.Similar questions
- List and discuss four different mechanisms by which vitamins A and D regulate gene expression.arrow_forwardGene expression may change in response to external cues through the activity of multiple signal transduction cascades. What is the primary mechanism that determines if a gene is expressed or not?arrow_forwardDescribe ways to achieve post-transcriptional control of gene expressionarrow_forward
- Choose ONE example of control of gene expression in eukaryotes and describe it in detail. Identify which of the five levels of regulation of gene expression your example represents and explain how your example benefits the cell in which it takes place.arrow_forwardDiscuss factors that might influence the activity of DNA-binding proteins (transcription factors) and bring about changes in gene expression. Include in your answer an example of a process that regulates gene expression at the level of transcriptionarrow_forwardExplain the role of allostery as being one of the regulating properties of gene expression.arrow_forward
- The most common type of regulation of gene expression occurs at the level of transcription. Name other types of gene regulation for gene expression in eukaryotic cells. Name types of gene regulation unique to eukaryotic cells versus prokaryotic cells.arrow_forwardChoose the statement that correctly characterizes regulated and/or constitutive gene expression. Regulated expression refers to gene expression that is either on or off, depending on the physiological or metabolic status of the cell. Constitutive expression refers to gene expression that is either on or off, depending on the physiological or metabolic status of the cell. Constitutive expression refers to gene expression that is always repressed in response to the absence of required nutrients or other metabolic molecules. Regulated expression refers to gene expression that is always on, regardless of the metabolic or physiological conditions in the cell. Regulated and constitutive expression are terms used to describe gene expression in prokaryotes only.arrow_forwardRegulation of gene expression in eukaryotes can occur: Group of answer choices at the post-transcriptional level, by changes in mRNA stability. all of these at the post-translational level, by modifications to activate proteins. at the transcriptional level, mediated by specific proteins called transcription factors. at the chromatin level, by changes in the state of condensation of chromatin.arrow_forward
- List steps in the process of gene expression thatpotentially could be regulated.arrow_forwardWhich of the following is NOT a reason cells regulate gene expression at a level other than the transcriptional level? Some proteins are only required in part of the cell and transcriptional control will only regulate the mRNA/protein throughout the cell. The core promoter for many genes is the same, so these genes will always be transcribed in the same cells. Differential gene expression in different cell types requires regulation of gene expression at levels other than transcription. Transcription and translation are realtively slow processes, so cells need to regulate gene expression post-transcriptionally if they require a fast change in expression of a gene. Not all cells are transcriptionally active (meaning they do not transcribe any genes), so these cells need to regulate gene expression post-transcriptionally.arrow_forwardExplain how DNA methylation could be used to regulate gene expression in a tissue-specific way. When and where would de novo methylation occur, and when would demethylation occur? What would occur in the cells that give rise to eggs and sperm?arrow_forward
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