BIOCHEMISTRY (LOOSELEAF)-W/ACCESS
9th Edition
ISBN: 9781319425784
Author: BERG
Publisher: Macmillan Higher Education
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Chapter 34, Problem 12P
Interpretation Introduction
Interpretation:
The examples of ion channels in vision, taste and hearing should be determined.
Concept introduction:
In the sensory system, the binding of the ligand to its receptors elicits different types of responses. These responses are exhibited by a series of cell and neural signalling pathways.
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- PLease ASAP. Thank you. Two pore (2P) domain K+ channels: What is the role of this channel? Is this channel voltage sensitive? Can this channel be inhibited by potassium channel blockers?arrow_forwardPlease ASAP. Thanku. Which of the following could not be a heteromeric ion channel? a. Voltage-gated sodium channel b. Voltage-gated potassium channel c. NMDR d. Acid-sensing ion channelarrow_forwardFrog poison. Batrachotoxin (BTX) is a steroidal alkaloid from the skin of Phyllobates terribilis, a poisonous Colombian frog (the source of the poison used on blowgun darts). In the presence of BTX, Na+Na* channels in an excised patch stay persistently open when the membrane is depolarized. They close when the membrane is repolarized. Which transition is blocked by BTX?arrow_forward
- Plesae ASAP. thanku Which of the following is not true about the glutamate family of ligand-gated ion channels? a. members are AMPA, kinase, and NMDA channels b. they are cation permable c. channels subunits have 3 full transmembrane doamins d. they require 5 subunits to amke a functional channelarrow_forwardPlease ASAP. Thanku. Which of the following requires a single subunit to make a functional pore? options:arrow_forwardPlease ASAP. Thank you.arrow_forward
- Please ASAP. Thank you.arrow_forwardOnly a few. Why do only a small number of sodium ions need to flow through the Na+Na* channel to change the membrane potential significantly?arrow_forwardNeed help. Plz explain During an action potential and for a few milliseconds after, is it possible to stimulate that region of a neuron to fire again? Explain your answer.arrow_forward
- Please ASAP. Thanku Which of the following is not true in ligand-gated ion channels? a. S4 segment moves in response to changes in membrane potential b. ligand binds to an agonist binding site c. conformational change occurs in subunits d. all of the above are truearrow_forwardPlease ASAP. Thank you.arrow_forwardAssighment. Create a diagram which illustrates the typical signalling mechanism of action of each of the four common classes of receptor (e.g. kinase-linked receptors etc.) and possible routes of communication (autocrine etc.). Your diagram should show the specific molecules involved, the mechanisms of signal transduction and indicate the different pathways that are activated. It should include a specific example of a receptor, ligand and signalling pathway for each general class. Include as wide a variety of ligands and modes of action as you can. For each of the examples describe the mechanism of action in the form below. DO NOT use any of the ligand-receptor combinations provide to you in the Learning Materials to date - research and create a diagram for a novel pathway instead!arrow_forward
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