Biochemistry (Looseleaf)
9th Edition
ISBN: 9781319114800
Author: BERG
Publisher: MAC HIGHER
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Question
Chapter 35, Problem 2P
Interpretation Introduction
Interpretation:
The mechanism used by B cells to increase antibody diversity should be determined.
Concept introduction:
Antigens refer to the substance which is foreign or external for the human body and arouses immune response either after forming a complex or alone with a larger molecule which has the capacity to bind T cell or antibody of the immune response.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Cold-Reacting Autoantibodies.
Most adult sera contain low titers of cold-reacting autoantibodies, most notably autoanti-I, autoanti-H, and autoanti-IH. These antibodies are usually IgM and of no clinical significance. They are troublesome in that they may interfere with the detection of significant antibodies, resulting in prolonged workups and delayed transfusions.Cold-reacting autoantibodies may be suspected when the screen cells, panel cells, and the autocontrol areall positive at the immediate spin phase and reactivity gets weaker or disappears with incubation at 37°C (Fig. 9–18).Certain cold autoantibodies activate complement and may be detected at the AHG phase when using complement-containing AHG reagent. These autoanti- bodies may be mistaken for weakly reacting IgG antibodies.Although it is not usually necessary to determine the specificity of the cold autoantibody, testing against additional cells may confirm its presence. Cord blood cells that lack the I antigen are of…
help.
Can Ab. Act as antigens? Explain why.
Chapter 35 Solutions
Biochemistry (Looseleaf)
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.Similar questions
- Need help. Please explain "droplet based immunoassay(immune assay)". Including "single droplet generates one phase of system".arrow_forwardCode_M02. Enumerate and explain the different types of hypersensitivity reactions. Give 2 examples each. ?arrow_forwardIn own word. What are the differences between contagious and communicable diseases? Explain with example?arrow_forward
- Asap . explain well pleasearrow_forwardgive correct option. Polyisocyanates are involved in the induction of the full spectrum of hypersensitivity responses and nonimmune inflammatory reactions including asthma. Which of the following statement is not correct with respect to these observations and impact on immunity? a. A person once sensitized to polyisocyanate can demonstrate group reactivity to this set of compounds. b. Individuals having an acute exposure to toluene diisocyanate is more likely to develop hypersensitivity then individuals chronically exposed to low vapor levels. c. A mechanism for this hypersensitivity is the toluene diisocyanate forms a covalent bond with proteins that are part of the airway resulting in the immune system developing a response to “self” proteins. d. Adaptive immunity can interact or “message” the Innate immune system to up or down regulate its expression. e. All of the statements are correct.arrow_forwarduple Choice. Write the letter of the correct response that best answers each question. 17. What type of immunity is responsible for agglutination of viruses? A. passive immunity B. cell mediated immunity C. nonspecific immunity D. antibody immunity 18. Which of the following best describes the immunity gained from a vaccine? A. nonspecific B. active C. passive D. artificial The dinarrow_forward
- True/False: The antibody protein has two functional domains, one for antigen binding and a second to confer specific effector functions. These two functional domains are encoded by the antibody light chain and antibody heavy chain polypeptides, respectively.arrow_forwardImmune systemarrow_forwardNeutralizing antibodies are effective at preventing infection or toxicity mediated by pathogens or their toxic products. In fact, nearly all vaccines currently in use function by eliciting neutralizing antibodies. One example is the tetanus vaccine, in which neutralizing antibodies are generated against an inactivated form of the tetanus toxin (the tetanus toxoid). The most important feature of a neutralizing antibody is having high affinity for the antigen. being efficient at activating the complement cascade. having a high degree of multivalency, such as being a pentamer or hexamer of immunoglobulin monomers. being present at a high concentration in the circulation. 0 0 0 0arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
BiochemistryBiochemistryISBN:9781319114671Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.Publisher:W. H. Freeman
Lehninger Principles of BiochemistryBiochemistryISBN:9781464126116Author:David L. Nelson, Michael M. CoxPublisher:W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul...BiochemistryISBN:9781118918401Author:Donald Voet, Judith G. Voet, Charlotte W. PrattPublisher:WILEY
BiochemistryBiochemistryISBN:9781305961135Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougalPublisher:Cengage Learning
BiochemistryBiochemistryISBN:9781305577206Author:Reginald H. Garrett, Charles M. GrishamPublisher:Cengage Learning
Fundamentals of General, Organic, and Biological ...BiochemistryISBN:9780134015187Author:John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. PetersonPublisher:PEARSON
Biochemistry
Biochemistry
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:W. H. Freeman
Lehninger Principles of Biochemistry
Biochemistry
ISBN:9781464126116
Author:David L. Nelson, Michael M. Cox
Publisher:W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul...
Biochemistry
ISBN:9781118918401
Author:Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:WILEY
Biochemistry
Biochemistry
ISBN:9781305961135
Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:Cengage Learning
Biochemistry
Biochemistry
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Cengage Learning
Fundamentals of General, Organic, and Biological ...
Biochemistry
ISBN:9780134015187
Author:John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:PEARSON
The Cell Membrane; Author: The Organic Chemistry Tutor;https://www.youtube.com/watch?v=AsffT7XIXbA;License: Standard youtube license