close solutoin list

Building Better Bones Tiffany, shown in FIGURE 35.10 , was born with multiple fractures in her arms and legs. By age six, she had undergone surgery to correct more than 200 bone fractures. Her fragile, easily broken bones are .symptoms or osteogenesis imperfecta (OI), a genetic disorder caused by a mutation in a gene for collagen. As bones develop, collagen forms a scaffold for deposition of mineralized bone tissue. The scaffold forms improperly in children with OI. FIGURE 35.10 also shows the results of a test of a new drug. Treated children, all less than two years old were compared to similarly affected children of the same age who were not treated with the drug. FIGURE 3.5.10 A clinical trial of a drug treatment for osteogenesis imperfect (OI) . OI affects the child shown at night. Nine children with received the drug. Six others were untreated Controls. Surface area of certain vertebrae were measured before and after treatment. Fractures occurring during the 12 months of the trial were also recorded. Do these results shown support the hypothesis that this drug, which slows bone breakdown, can increase bone growth and reduce fractures in young children with OI?

BuyFind

Biology: The Unity and Diversity o...

15th Edition
Cecie Starr + 3 others
Publisher: Cengage Learning
ISBN: 9781337408332
BuyFind

Biology: The Unity and Diversity o...

15th Edition
Cecie Starr + 3 others
Publisher: Cengage Learning
ISBN: 9781337408332

Solutions

Chapter
Section
Chapter 35, Problem 4DAA
Textbook Problem

Building Better Bones Tiffany, shown in FIGURE 35.10, was born with multiple fractures in her arms and legs. By age six, she had undergone surgery to correct more than 200 bone fractures. Her fragile, easily broken bones are .symptoms or osteogenesis imperfecta (OI), a genetic disorder caused by a mutation in a gene for collagen. As bones develop, collagen forms a scaffold for deposition of mineralized bone tissue. The scaffold forms improperly in children with OI. FIGURE 35.10 also shows the results of a test of a new drug. Treated children, all less than two years old were compared to similarly affected children of the same age who were not treated with the drug.

Chapter 35, Problem 4DAA, Building Better Bones Tiffany, shown in FIGURE 35.10, was born with multiple fractures in her arms , example  1

Chapter 35, Problem 4DAA, Building Better Bones Tiffany, shown in FIGURE 35.10, was born with multiple fractures in her arms , example  2

Chapter 35, Problem 4DAA, Building Better Bones Tiffany, shown in FIGURE 35.10, was born with multiple fractures in her arms , example  3

FIGURE 3.5.10 A clinical trial of a drug treatment for osteogenesis imperfect (OI). OI affects the child shown at night. Nine children with received the drug. Six others were untreated Controls. Surface area of certain vertebrae were measured before and after treatment. Fractures occurring during the 12 months of the trial were also recorded.

Do these results shown support the hypothesis that this drug, which slows bone breakdown, can increase bone growth and reduce fractures in young children with OI?

Expert Solution

Want to see this answer and more?

Experts are waiting 24/7 to provide step-by-step solutions in as fast as 30 minutes!*

See Solution

*Response times vary by subject and question complexity. Median response time is 34 minutes and may be longer for new subjects.

Additional Science Textbook Solutions

Find more solutions based on key concepts
Show solutions
On average, young men in the United States obtain percent of their calories from beverages. a. 12 b. 22 c. 32 d...

Nutrition: Concepts and Controversies - Standalone book (MindTap Course List)

Where in a prokaryotic cell is DNA found? How is that DNA organized?

Biology: The Dynamic Science (MindTap Course List)

25-47 What is the purpose of piRNA?

Introduction to General, Organic and Biochemistry

Describe two biological roles served by the lecithins.

Chemistry for Today: General, Organic, and Biochemistry

A 0.300-kg puck, initially at rest on a horizontal, frictionless surface, is struck by a 0.200-kg puck moving i...

Physics for Scientists and Engineers, Technology Update (No access codes included)

Of what commercial importance are marine algae and plants?

Oceanography: An Invitation To Marine Science, Loose-leaf Versin