Campbell Biology In Focus
Campbell Biology In Focus
2nd Edition
ISBN: 9780134203072
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece
Publisher: PEARSON
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Chapter 35.3, Problem 1CC
Summary Introduction

To determine:

The type of disorder of myasthenia gravis. In this condition, antibodies bind to and block certain receptors on muscle cells, preventing muscle contraction.

Introduction:

This condition called myasthenia gravis weakens the skeletal muscles and causes difficulty in the movement of muscles and leads to the weakness. The destruction of nerves, results in the difficulty in locomotion and movement.

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Myasthenia gravis is an autoimmune disorder. Tag the statement true or false.
Define type II hypersensitivity? Describe the immunological processes which underlie this condition. Outline the clinical symptoms and signs seen in Myasthenia Gravis and Graves’ disease. Explain how type II hypersensitivity results in this clinical picture.
A nerve conduction velocity test measures nerve conduction velocity. In this test, an electrical stimulus is applied to a peripheral nerve and the length of time it takes for the corresponding muscle to contract is measured. Because the length of the nerve from stimulus point to muscle and the time it takes for the muscle to contract are both known, NCV can be calculated. This test result is helpful in distinguishing between different types of pathologies. For example, a patient with muscle weakness is being tested by a physician. There are three possible sources of the weakness: Disease of the muscle itself such as muscular dystrophy. In this condition, normal muscle tissue is replaced by adipose tissue and the muscle becomes incapable of contraction. Disease at the neuromuscular junction (NMJ) such as myasthenia gravis. This condition is described in the Skeletal Muscle Histology exercise and results from damage to the acetylcholine receptors on the muscle end plate. Disease…
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