Introduction:
Cell division occurs through a highly regulated series of steps called the cell cycle. The genetic stability of the cell is maintained by this process, while helping the cell to multiply. Multiplication may be necessary during growth, regeneration, and repair. But uncontrolled entry into various stages of cell cycle may lead to formation of dysfunctional cancer cells. Thus, strict regulation of entry into the stages is essential. This is done at cell cycle checkpoints, where the cell decides whether to enter the next stage or halt the process of cell division. Many factors may influence this regulation, like presence of growth factors, DNA damage, availability of nutrients, etc.
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