Concept explainers
Introduction:
DNA is a genetic material, consisting of a long stretch of
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- The genetic disorder sickle-cell anemia occurs when the amino acid valine takes the place of glutamate during translation of a hemoglobin chain. Using the table of codons below, determine the mutation in DNA that produces this disorder. 1st position ✓ U C A G Select one: U C serine phenylalanine phenylalanine serine leucine serine leucine serine leucine leucine leucine leucine isoleucine isoleucine isoleucine methionine Table of mRNA Codons 2nd position valine valine valine valine proline proline proline proline alanine alaninc alanine alanine A tyrosine tyrosine a. CUC changes to C AG b. GAA changes to GUU c. CTT changes to CAT d. C A G changes to CTC stop stop threonine asparagine threonine asparagine threonine threonine histidine histidine arginine arginine glutamine arginine glutamine arginine lysine lysine G cysteine cysteine stop tryptophan aspartate aspartate glutamate glutamate serine serine arginine arginine glycine glycine glycine glycine 3rd position DCMO U С A G U C A G…arrow_forwardwhat does the Hexa protein domain depict? (in relation with tay sachs disease)arrow_forwardCan you spell your name (or someone else's) using the one-letter amino acid abbreviations? If so, construct an mRNA sequence that encodes your "protein" name.arrow_forward
- A portion of the sequence from the DNA coding strand of the chick ovalbumin gene is shown. Determine the partial amino acid sequence of the encoded protein. CTCAGAGTTCACCATGGGCTCCATCGGTGCAGCAAGCATGGAA-(1104 bp)-TTCTTTGGCAGATGTGTTTCCCCTTAAAAAGAA Enter the 3-letter abbreviation for each amino acid in sequence, separated with dashes, and no spaces (example: xxx-xxx-XXX-XXX...) The amino acid sequence is .1104bp..…........arrow_forwardA gene contains 30% thymine. What is the percentage of pyrimidines present in this segment? Explain.arrow_forwardplease identify structure information about this gene which is adgrg1/gpr56. You can identify anything about the molecule including chains, atoms, etc.arrow_forward
- Why does Valerie's blood from her peripheral, tumor and breast samples all show bands of DNA that are 3000 bases and 1282 bases long?arrow_forward5'GGT ACG TTG GGG CTC CAT3' This sequence is transcribed and translated. Write the resulting amino acid sequence using the 3 letter code. Write the answer in a all capital letters. Leave a space between the amino acids. Do not write 5' and 3'. 5'GGT ACG TTG GGG CTC CAT3' This sequence is transcribed and translated. If the G in Bold changes to a T, then the result will be A) A nonsense mutation B) A frameshift mutation C) A silent substitution D) A missense mutation 5'GGT ACG TTG GGG CTC CAT3' This sequence is transcribed and translated. If the G in Bold changes to a A, then the result will be A) A nonsenese mutation B) A frameshift mutation C) A silent substitution D) A missense mutationarrow_forwardWhat is the meaning of the statement “The code is redundant but not ambiguous?”.arrow_forward
- The human genome has approximately 30,000 genes, but human cells can produce over 100,000 different polypeptides. Explain how this is possiblearrow_forwardWhat does the White gene code for?arrow_forwardHow many base-pairs would have to be deleted in a mutational event to eliminate a single amino acid from a protein and not change the rest of the protein? You must enter a whole number (no text)arrow_forward
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