Essentials of Genetics Plus Mastering Genetics with eText -- Access Card Package (9th Edition) (Klug et al. Genetics Series)
9th Edition
ISBN: 9780134047201
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Textbook Question
Chapter 4, Problem 30PDQ
The specification of the anterior-posterior axis in Drosophila embryos is initially controlled by various gene products that are synthesized and stored in the mature egg following oogenesis. Mutations in these genes result in abnormalities of the axis during embryogenesis, illustrating maternal effect. How do such mutations vary from those involved in organelle heredity that illustrate extranuclear inheritance? Devise a set of parallel crosses and expected outcomes involving mutant genes that contrast maternal effect and organelle heredity.
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In drosophila, a recessive mutation (m-) of a maternal effect gene results in an abnormal phenotype wherein homozygous (m-m-) females produce eggs that cannot support embryonic development. Homozygous (m-m-) males, however, can still produce viable sperm. Using m+ to denote a normal gene, determine the genotypes and phenotypes of the F1s produce by a cross between a heterozygous female and a recessive male. From the offspring, backcross the recessive female with the paternal strain. What are the genotypes and phenotypes of the F2s? Show COMPLETE cross for both cases.
If m-m- females produce useless eggs, then how are m-m- produced?
A maternal effect gene in Drosophila, called torso, is found as a recessive allele that prevents the correct development of anterior- and posterior-most structures. A wild-type (homozygous) male is crossed to a female of unknown genotype. This mating produces 100% larva that are missing their anterior- and posterior-most structures and therefore die during early development. What is the genotype and phenotype of the female fly in this cross? What are the genotypes and phenotypes of the female fly’s parents? Show COMPLETE cross.
A maternal effect gene in Drosophila, called torso, is found as a recessive allele that prevents the correct development of anterior- and posterior-most structures. A wild-type (homozygous) male iscrossed to a female of unknown genotype. This mating produces 100% larva that are missing theiranterior- and posterior-most structures and therefore die during early development.
What is the genotype and phenotype of the female fly in this cross? What are the genotypes andphenotypes of the female fly’s parents? Show COMPLETE cross.
Maternal genotype:Paternal genotype:F1 genotype:F1 phenotype:
Chapter 4 Solutions
Essentials of Genetics Plus Mastering Genetics with eText -- Access Card Package (9th Edition) (Klug et al. Genetics Series)
Ch. 4 - CASE STUDY | But he isn't deaf Researching their...Ch. 4 -
CASE STUDY | But he isn’t deaf
Researching...Ch. 4 - CASE STUDY | But he isn't deaf Researching their...Ch. 4 - HOW DO WE KNOW? In this chapter, we focused on...Ch. 4 - Review the Chapter Concepts list on page 53. These...Ch. 4 - In Shorthorn cattle, coat color may be red, white,...Ch. 4 -
4. With regard to the ABO blood types in humans,...Ch. 4 - In foxes, two alleles of a single gene, P and p,...Ch. 4 - Three gene pairs located on separate autosomes...Ch. 4 - As in the plants of Problem 6, color may be red,...
Ch. 4 -
8. The following genotypes of two independently...Ch. 4 - Given the inheritance pattern of coat color in...Ch. 4 - A husband and wife have normal vision, although...Ch. 4 - In humans, the ABO blood type is under the control...Ch. 4 - In goals, development of the beard is due to a...Ch. 4 -
13. In cats, orange coal color is determined by...Ch. 4 - In Drosophila, an X-linked recessive mutation,...Ch. 4 - Another recessive mutation in Drosophila, ebony...Ch. 4 - While vermilion is X-linked in Drosophila and...Ch. 4 - In pigs, coat color may be sandy, red, or white. A...Ch. 4 - A geneticist from an alien planet that prohibits...Ch. 4 - In another cross, the frog geneticist from Problem...Ch. 4 - In cattle, coats may be solid white, solid black,...Ch. 4 - Consider the following three pedigrees, all...Ch. 4 - Labrador retrievers may be black, brown, or golden...Ch. 4 - Three autosomal recessive mutations in Drosophila,...Ch. 4 -
24. Horses can be cremello (a light cream...Ch. 4 - Pigment in the mouse is produced only when the C...Ch. 4 - Five human matings numbered 1–5 are shown in the...Ch. 4 - Two mothers give birth to sons at the same time at...Ch. 4 - In Dexter and Kerry cattle, animals may be polled...Ch. 4 - What genetic criteria distinguish a case of...Ch. 4 -
30. The specification of the anterior-posterior...Ch. 4 - The maternal-effect mutation bicoid(bcd)is...Ch. 4 -
32. Students taking a genetics exam were...Ch. 4 - In four o'clock plants, many flower colors are...Ch. 4 - Prob. 34PDQ
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- What possible conclusions can be drawn from the observations that in male Drosophila, no crossing over occurs, and that during meiosis, synaptonemal complexes are not seen in males but are observed in females where crossing over occurs?arrow_forwardIn drosophila, a recessive mutation (m-) of a maternal effect gene results in an abnormal phenotype wherein homozygous (m-m-) females produce eggs that cannot support embryonic development. Homozygous (m-m-) males, however, can still produce viable sperm. (A) Using m+ to denote a normal gene, determine the genotypes and phenotypes of the F1s produce by a cross between a heterozygous female and a recessive male. (B) From the offspring, backcross the recessive female with the paternal strain. What are the genotypes and phenotypes of the F2s? (C) If m-m- females produce useless eggs, then how are m-m- produced?arrow_forwardThe locations of six deletions have been mapped to a Drosophila chromosome, as shown in the following deletion map. Recessive mutations a, b, c, d, e, and f are known to be located in the same region as the deletions, but the order of the mutations on the chromosome is not known.arrow_forward
- It is assumed that in Drosophila the following genotypes produce phenotypes. َA- B- = Red color A- bb = Plum color aa B- = Magenta color aa bb = White color The third latent genotype, cc, kills homozygous Plums, but has no effect on other genotypes. Also, genotype C- does not produce a large phenotype. If first-generation Drosophilas are heterozygous for all of these genes and interbreed, what phenotypic ratios are expected in society?arrow_forwarda. If an individual who is homozygous for the mutation found in individual 2 and heterozygous for the mutation found in individual 4 marries an individual who is homozygous for the mutation found in individual 4 and heterozygous for the mutation found in individual 2, what will be the phenotype of their children? b. List the intermediate that would build up in each of the types of children who could not produce protein E.arrow_forwardWhy is it that mutations in bicoid and nanos exhibit genetic maternal effect in Drosophila (a mutation in the maternal parent produces a phenotype that shows up in the offspring), but mutations in runt and gooseberry do not?arrow_forward
- What would be the most likely effect on development of puncturing the posterior end of a Drosophila egg, allowing a small amount of cytoplasm to leak out, and then injecting that cytoplasm into the anterior end of another egg?arrow_forwardA new recessive mutant allele doesn’t show pseudodominance with any of the deletions that span Drosophilachromosome 2. What might be the explanation?arrow_forwardIn Drosophila melanogaster body color is controlled by one gene while wing shape is controlled by a second gene. Gray body color is dominant to black body color, and normal wings are dominant to vestigial wings. Flies homozygous for gray body color and vestiial wing are crossed with flies homozygous for black body color and normal wings Compare the possible F2generation genotypes and phenotypes and proportions if these two traits are autosomally linked in comparison to the non-linked How does your answer change if one of the original parents is homozygous for gray body color and normal wings while the other has black body color and vestigial wingsarrow_forward
- In a cross in Drosophila involving the X-linked recessive eye mutationwhite and the autosomally linked recessive eye mutation sepia(resulting in a dark eye), predict the F1 and F2 results of crossingtrue-breeding parents of the following phenotypes:(a) white females * sepia males(b) sepia females * white malesNote that white is epistatic to the expression of sepiaarrow_forwardA maternal effect gene in Drosophila, called torso, occurs as a functionalallele (torso+) and a nonfunctional, recessive allele (torso−)that prevents the correct development of anterior- and posterior-moststructures. A wild-type male (torso+torso+) is crossed to a female ofunknown genotype. This cross produces offspring (larva) that are allmissing their anterior- and posterior-most structures and therefore die during early development. What are the genotype and the phenotypeof the female fly in this cross? What are the genotypes andphenotypes of the female fly’s parents?arrow_forwardIn Drosophila subobscura, the presence of a recessive gene called grandchildless (gs) causes the offspring of homozygous females, but not those of homozygous males, to be sterile. Can you offer an explanation as to why females and not males are affected by the mutant gene?arrow_forward
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