Developmental Biology
11th Edition
ISBN: 9781605355979
Author: Gilbert
Publisher: Oxford University Press
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Chapter 4, Problem 3DQ
Summary Introduction
To review:
The difference in pathways of Wnt/β-catenin, calcium, and PCP. The examination of meaningful pathway interactions among all the paracrine factors (Wnt, Hedgehog, FGF, BMP, etc).
Introduction:
Paracrine factors often act as morphogens for induction of numerous organs and can be grouped into one of four major families based on structure:
The fibroblast growth factor (FGF) family
The Hedgehog family
The Wnt family
The TGF-β superfamily, the activin family, the bone morphogenetic proteins (BMPs), the nodal proteins, the Vg1 family.
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Paper link - https://www.jneurosci.org/content/40/8/1756.long
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QUESTION:-
Using specific examples, discuss the versatility of different subtypes of GPCRs for the hormone epinephrine.
Question 19
Which expenmental outcomes collactively support the conclusion that an
embryonio cell has a specified level of commitment? (select all correct answers!
A )When the cell is removed and cultured with a chemical inhibitor of the TGFbeta signaling pathway it continues to differenfiate into muscle
B)When the cell is removed and cultured with a chemical inhibitor of the TGFbeta signaling pathway it differentiates into neurons rather than muscla
C )When the embryonic cell is removed and cultured in neutral medium it's descendents consistently differentiate into muscle
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Chapter 4 Solutions
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