Explanation Alzheimer affected person suffer from memory loss, and in later stages it remove long-held memories. This is caused due to the destruction of neurons in the brain. Neuron degeneration is caused by plaques formed by two different proteins, one called amyloid β, or Aβ, and the other one called tau. Aβ is derived from a larger protein called amyloid beta precursor protein (APP). APP is a membrane-bound protein, partly found inside a neuron and partly outside it...

8th Edition

ISBN: 9781285429106

Author: Campbell, Mary K., FARRELL, Shawn O.

Publisher: Cengage Learning,

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Question

Chapter 4, Problem 62RE

Interpretation Introduction

Interpretation:

The proteins involved in the formation of the destructive plaques found in Alzheimer’s disease.

Concept Introduction:

Alzheimer disease is a neurodegenerative disease, which starts slowly and gets worse with the passage of time. This disease is characterized by the presence of extracellular amyloid plaques and intracellular neurofibrillary tangles, resulting in neuronal dysfunction and cell death. Amyloid is characterized by general term for protein fragments that the body produces normally. Amyloid plaques are present between nerve cells (neurons) in the brain.

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Chapter 4, Problem 61RE

Chapter 4, Problem 63RE

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Solution Summary: The author describes Alzheimer disease as a neurodegenerative disease characterized by amyloid plaques and intracellular neurofibrillary tangles, resulting in neuronal dysfunction and cell death.

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