CAMPBELL'S BIOLOGY 12E PERUSALL
CAMPBELL'S BIOLOGY 12E PERUSALL
12th Edition
ISBN: 9780135858080
Author: Urry
Publisher: PERUSALL
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Chapter 41.5, Problem 3CC
Summary Introduction

To explain: The effect of insulinomas on blood glucose levels and liver functions.

Introduction:

Insulinomas are cancerous insulin-producing beta cells of pancreatic islets of Langerhans. These tumors lack response to feedback mechanisms and secret insulin even when there is a low blood glucose level in the body.

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5. There is an expression: diabetes mellitus is «hunger among abundance. What metabolic changes in diabetes confirm the validity of this statement? For answer: 9.8. Metabolic Changes in Diabetes Mellitus 535 a) list the main causes of metabolic changes in IDDM; b) enumerate the tissues with the main energy sources metabolism procceding according to this type of starvation; c) name the metabolic pathways that are activated and inhibited in these tissues, and explain why; d) list the symptoms of diabetes mellitus, that reflect such metabolic changes; c) draw a diagram of one of the mctabolic pathways that is activated in the liver under these conditions and explain the consequences of such activation.
Match the molecule involved in insulin signaling with what it does insulin receptor [Choose ] [Choose] physically pushes glucose out of the cell physically brings glucose into the cell binds to insulin and sends signal to cell a protein hormone that signals cells to import glucose signals cells to export glucose a carbohydrate taken into cells as an energy source glucose insulin glucose transporter [ Choose ] 近
. What would be the effect of a mutation in the gene for PTP1B (protein tyrosine phosphatase 1B) that inactivated the enzyme in a person who has type 2 diabetes?
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